Inbound Relationships |
Type |
Active |
Source |
Characteristic |
Refinability |
Group |
A rare mitochondrial oxidative phosphorylation disorder with complex I and IV deficiency characterized by lactic acidosis, hypotonia, hypertrophic cardiomyopathy and global developmental delay. Other clinical features include feeding difficulties, failure to thrive, seizures, optic atrophy and ataxia. |
Finding site |
True |
Myocardium structure |
Inferred relationship |
Some |
1 |
Congenital cataract - hypertrophic cardiomyopathy - mitochondrial myopathy (CCM) is a mitochondrial disease characterized by cataracts, hypertrophic cardiomyopathy, muscle weakness and lactic acidosis after exercise. |
Finding site |
True |
Myocardium structure |
Inferred relationship |
Some |
2 |
Cardiomyopathy-hypotonia-lactic acidosis syndrome is characterized by hypertrophic cardiomyopathy, muscular hypotonia and the presence of lactic acidosis at birth. It has been described in two sisters (both of whom died within the first year of life) from a nonconsanguineous Turkish family. The syndrome is caused by a homozygous point mutation in the exon 3A of the SLC25A3 gene encoding a mitochondrial membrane transporter. |
Finding site |
True |
Myocardium structure |
Inferred relationship |
Some |
2 |
Cardiomyopathy and renal anomaly syndrome (disorder) |
Finding site |
True |
Myocardium structure |
Inferred relationship |
Some |
1 |
Polyglucosan body myopathy type 1 is a rare, genetic, glycogen storage disorder characterized by polyglucosan accumulation in various tissues, manifesting with progressive proximal muscle weakness in the lower limbs and rapidly progressive, usually dilated, cardiomyopathy. Hepatic involvement and growth retardation may be associated. Early-onset immunodeficiency and autoinflammation, presenting with recurrent bacterial infections, have also been reported. |
Finding site |
True |
Myocardium structure |
Inferred relationship |
Some |
2 |
Combined oxidative phosphorylation defect type 17 is a rare, genetic, mitochondrial disorder due to a defect in mitochondrial protein synthesis characterized by infantile onset of severe hypertrophic cardiomyopathy (that occasionally progresses to dilated cardiomyopathy) associated with failure to thrive, global development delay, muscular hypotonia, elevated serum lactate and complex I deficiency in skeletal muscle biopsy. Intellectual disability, pericardial effusion and a mild cardiac phenotype have been also reported. |
Finding site |
True |
Myocardium structure |
Inferred relationship |
Some |
1 |
Myocardial infarction due to demand ischemia (disorder) |
Finding site |
True |
Myocardium structure |
Inferred relationship |
Some |
1 |
Myocarditis caused by Rickettsia |
Finding site |
True |
Myocardium structure |
Inferred relationship |
Some |
1 |
Myocarditis caused by Candida |
Finding site |
True |
Myocardium structure |
Inferred relationship |
Some |
1 |
Myocarditis caused by Aspergillus (disorder) |
Finding site |
True |
Myocardium structure |
Inferred relationship |
Some |
1 |
Measles myocarditis |
Finding site |
True |
Myocardium structure |
Inferred relationship |
Some |
2 |
Myopericarditis (disorder) |
Finding site |
True |
Myocardium structure |
Inferred relationship |
Some |
1 |
Infection causing myoendocarditis (disorder) |
Finding site |
True |
Myocardium structure |
Inferred relationship |
Some |
2 |
Myocarditis co-occurrent with human immunodeficiency virus infection |
Finding site |
True |
Myocardium structure |
Inferred relationship |
Some |
1 |
Positron emission tomography myocardial rest imaging using rubidium-82 (procedure) |
Procedure site - Direct (attribute) |
True |
Myocardium structure |
Inferred relationship |
Some |
1 |
Positron emission tomography with computed tomography myocardial rest imaging using rubidium-82 (procedure) |
Procedure site - Direct (attribute) |
True |
Myocardium structure |
Inferred relationship |
Some |
1 |
Positron emission tomography with computed tomography myocardial rest imaging using rubidium-82 (procedure) |
Procedure site - Direct (attribute) |
True |
Myocardium structure |
Inferred relationship |
Some |
2 |
Positron emission tomography with computed tomography myocardial stress imaging using rubidium-82 (procedure) |
Procedure site - Direct (attribute) |
True |
Myocardium structure |
Inferred relationship |
Some |
1 |
Positron emission tomography with computed tomography myocardial stress imaging using rubidium-82 (procedure) |
Procedure site - Direct (attribute) |
True |
Myocardium structure |
Inferred relationship |
Some |
2 |
Positron emission tomography myocardial stress imaging using rubidium-82 (procedure) |
Procedure site - Direct (attribute) |
True |
Myocardium structure |
Inferred relationship |
Some |
1 |
Cardiomyopathy due to diabetes mellitus (disorder) |
Finding site |
True |
Myocardium structure |
Inferred relationship |
Some |
1 |
Rheumatic cardiomyopathy (disorder) |
Finding site |
True |
Myocardium structure |
Inferred relationship |
Some |
2 |
Acute ST segment elevation myocardial infarction due to proximal left anterior descending coronary artery occlusion |
Finding site |
True |
Myocardium structure |
Inferred relationship |
Some |
2 |
Acute ST segment elevation myocardial infarction due to mid left anterior descending coronary artery occlusion |
Finding site |
True |
Myocardium structure |
Inferred relationship |
Some |
2 |
Acute ST segment elevation myocardial infarction due to distal left anterior descending coronary artery occlusion |
Finding site |
True |
Myocardium structure |
Inferred relationship |
Some |
2 |
A rare hereditary Transthyretin (TTR)-related systemic amyloidosis (ATTR) with predominant cardiac involvement resulting from myocardial infiltration of abnormal amyloid protein. |
Finding site |
True |
Myocardium structure |
Inferred relationship |
Some |
1 |
Acute ST segment elevation myocardial infarction due to occlusion of anterior descending branch of left coronary artery |
Finding site |
True |
Myocardium structure |
Inferred relationship |
Some |
1 |
Myocardial ischemia of newborn |
Finding site |
True |
Myocardium structure |
Inferred relationship |
Some |
1 |
Acute myocardial ischemia (disorder) |
Finding site |
True |
Myocardium structure |
Inferred relationship |
Some |
1 |
Chronic myocardial ischemia (disorder) |
Finding site |
True |
Myocardium structure |
Inferred relationship |
Some |
1 |
Myocardial ischemia (disorder) |
Finding site |
True |
Myocardium structure |
Inferred relationship |
Some |
1 |
Myocardial ischemia during surgery (disorder) |
Finding site |
True |
Myocardium structure |
Inferred relationship |
Some |
2 |
Acute ST segment elevation myocardial infarction due to occlusion of septal branch of anterior descending branch of left coronary artery (disorder) |
Finding site |
True |
Myocardium structure |
Inferred relationship |
Some |
2 |
Fetal myocarditis |
Finding site |
True |
Myocardium structure |
Inferred relationship |
Some |
1 |
Acute ST segment elevation myocardial infarction due to occlusion of diagonal branch of anterior descending branch of left coronary artery (disorder) |
Finding site |
True |
Myocardium structure |
Inferred relationship |
Some |
1 |
Acute ST segment elevation myocardial infarction due to occlusion of intermediate artery |
Finding site |
True |
Myocardium structure |
Inferred relationship |
Some |
1 |
Magnetic resonance imaging of chest and myocardium (procedure) |
Procedure site - Direct (attribute) |
True |
Myocardium structure |
Inferred relationship |
Some |
1 |
Single photon emission computed tomography of myocardial perfusion with computed tomography |
Procedure site - Direct (attribute) |
True |
Myocardium structure |
Inferred relationship |
Some |
1 |
Single photon emission computed tomography of myocardial perfusion with computed tomography |
Procedure site - Direct (attribute) |
True |
Myocardium structure |
Inferred relationship |
Some |
2 |
Positron emission tomography using nitrogen 13 ammonia with computed tomography myocardial rest study (procedure) |
Procedure site - Direct (attribute) |
True |
Myocardium structure |
Inferred relationship |
Some |
2 |
PET myocardial glucose metabolism study |
Procedure site - Direct (attribute) |
True |
Myocardium structure |
Inferred relationship |
Some |
1 |
PET myocardial rest study using N13 ammonia |
Procedure site - Direct (attribute) |
True |
Myocardium structure |
Inferred relationship |
Some |
1 |
Cardiotoxicity |
Finding site |
True |
Myocardium structure |
Inferred relationship |
Some |
1 |
Cardiomyopathy due to storage disease |
Finding site |
True |
Myocardium structure |
Inferred relationship |
Some |
2 |
Cardiomyopathy due to connective tissue disease |
Finding site |
True |
Myocardium structure |
Inferred relationship |
Some |
2 |
Acute ST segment elevation myocardial infarction due to occlusion of proximal portion of right coronary artery (disorder) |
Finding site |
True |
Myocardium structure |
Inferred relationship |
Some |
1 |
Acute ST segment elevation myocardial infarction due to occlusion of distal portion of right coronary artery (disorder) |
Finding site |
True |
Myocardium structure |
Inferred relationship |
Some |
1 |
Acute ST segment elevation myocardial infarction due to occlusion of mid portion of right coronary artery (disorder) |
Finding site |
True |
Myocardium structure |
Inferred relationship |
Some |
1 |
Acute ST segment elevation myocardial infarction due to occlusion of marginal branch of right coronary artery |
Finding site |
True |
Myocardium structure |
Inferred relationship |
Some |
1 |
Acute ST segment elevation myocardial infarction due to occlusion of posterior lateral branch of right coronary artery (disorder) |
Finding site |
True |
Myocardium structure |
Inferred relationship |
Some |
1 |
Acute ST segment elevation myocardial infarction due to occlusion of posterior descending branch of right coronary artery |
Finding site |
True |
Myocardium structure |
Inferred relationship |
Some |
1 |
PET myocardial stress study using N13 ammonia |
Procedure site - Direct (attribute) |
True |
Myocardium structure |
Inferred relationship |
Some |
1 |
Myocarditis due to COVID-19 |
Finding site |
True |
Myocardium structure |
Inferred relationship |
Some |
1 |
Cardiomyopathy due to COVID-19 |
Finding site |
True |
Myocardium structure |
Inferred relationship |
Some |
1 |
Myocarditis due to childhood type dermatomyositis (disorder) |
Finding site |
True |
Myocardium structure |
Inferred relationship |
Some |
1 |
Myocarditis due to Chaga disease |
Finding site |
True |
Myocardium structure |
Inferred relationship |
Some |
1 |
Hypertrophic cardiomyopathy due to glycogen storage disease |
Finding site |
True |
Myocardium structure |
Inferred relationship |
Some |
1 |
Dilated cardiomyopathy due to mitochondrial disease |
Finding site |
True |
Myocardium structure |
Inferred relationship |
Some |
1 |
Myocarditis due to autoimmune disease (disorder) |
Finding site |
True |
Myocardium structure |
Inferred relationship |
Some |
1 |
Infiltrative cardiomyopathy |
Finding site |
True |
Myocardium structure |
Inferred relationship |
Some |
1 |
Hypertrophic cardiomyopathy due to lysosomal disease |
Finding site |
True |
Myocardium structure |
Inferred relationship |
Some |
1 |
Myocardial infarction with non-obstructive coronary artery (disorder) |
Finding site |
True |
Myocardium structure |
Inferred relationship |
Some |
1 |
Dilated cardiomyopathy due to carnitine deficiency (disorder) |
Finding site |
True |
Myocardium structure |
Inferred relationship |
Some |
1 |
Myocarditis due to Kawasaki disease (disorder) |
Finding site |
True |
Myocardium structure |
Inferred relationship |
Some |
1 |
Fetal hypertrophic cardiomyopathy due to maternal diabetes mellitus |
Finding site |
True |
Myocardium structure |
Inferred relationship |
Some |
1 |
Fetal hypertrophic cardiomyopathy (disorder) |
Finding site |
True |
Myocardium structure |
Inferred relationship |
Some |
1 |
Fetal hypertrophic cardiomyopathy due to twin to twin transfusion syndrome (disorder) |
Finding site |
True |
Myocardium structure |
Inferred relationship |
Some |
2 |
Fetal hypertrophic cardiomyopathy associated with renal disease |
Finding site |
True |
Myocardium structure |
Inferred relationship |
Some |
2 |
Hypertrophic cardiomyopathy due to Friedreich ataxia |
Finding site |
True |
Myocardium structure |
Inferred relationship |
Some |
1 |
Hypertrophic cardiomyopathy due to neuromuscular disorder |
Finding site |
True |
Myocardium structure |
Inferred relationship |
Some |
1 |
Hypertrophic cardiomyopathy due to hyperthyroidism |
Finding site |
True |
Myocardium structure |
Inferred relationship |
Some |
1 |
Hypertrophic cardiomyopathy due to disorder |
Finding site |
True |
Myocardium structure |
Inferred relationship |
Some |
1 |
Dilated cardiomyopathy due to lysosomal storage disease (disorder) |
Finding site |
True |
Myocardium structure |
Inferred relationship |
Some |
1 |
Dilated cardiomyopathy caused by anthracycline |
Finding site |
True |
Myocardium structure |
Inferred relationship |
Some |
1 |
Sarcoid heart muscle disease |
Finding site |
True |
Myocardium structure |
Inferred relationship |
Some |
2 |
Disorder of fetal myocardium (disorder) |
Finding site |
True |
Myocardium structure |
Inferred relationship |
Some |
1 |
Fetal cardiomyopathy |
Finding site |
True |
Myocardium structure |
Inferred relationship |
Some |
1 |
Fetal dilated cardiomyopathy |
Finding site |
True |
Myocardium structure |
Inferred relationship |
Some |
1 |
Fetal heart failure with myocardial hypertrophy (disorder) |
Finding site |
True |
Myocardium structure |
Inferred relationship |
Some |
1 |
Acute myocardial infarction due to occlusion of circumflex branch of left coronary artery (disorder) |
Finding site |
True |
Myocardium structure |
Inferred relationship |
Some |
1 |
Acute ST segment elevation myocardial infarction due to occlusion of circumflex branch of left coronary artery |
Finding site |
True |
Myocardium structure |
Inferred relationship |
Some |
1 |
Myocardial infarction due to atherothrombotic coronary artery disease (disorder) |
Finding site |
True |
Myocardium structure |
Inferred relationship |
Some |
1 |
Myocarditis caused by Neisseria gonorrhoeae (disorder) |
Finding site |
True |
Myocardium structure |
Inferred relationship |
Some |
1 |
Thyrotoxic cardiomyopathy |
Finding site |
True |
Myocardium structure |
Inferred relationship |
Some |
1 |
Endomyocardial fibrosis (disorder) |
Finding site |
True |
Myocardium structure |
Inferred relationship |
Some |
2 |
Restrictive cardiomyopathy with endomyocardial fibrosis (disorder) |
Finding site |
True |
Myocardium structure |
Inferred relationship |
Some |
2 |
Tropical endomyocardial fibrosis is a restrictive cardiopathy, occurring almost exclusively in children and young adults in tropical and subtropical regions, characterized by endocardial fibrosis, affecting the apices and the inflow tract of the right or left ventricle (or both) and manifesting with a restrictive cardiomyopathy and atrioventricular regurgitation leading to severe pulmonary hypertension, very high systemic venous pressure and congestive cardiac failure. Suspected etiologies include helminth and protozoal infestation and malnutrition. |
Finding site |
True |
Myocardium structure |
Inferred relationship |
Some |
2 |
Glycogen storage disease due to muscle and heart glycogen synthase deficiency is characterized by muscle and heart glycogen deficiency. It has been described in three siblings (two brothers and their younger sister). The older brother died at 10.5 years of age as a result of sudden cardiac arrest and the younger brother presented with hypertrophic cardiomyopathy, abnormal heart rate and blood pressure during exercise, and muscle fatigability. The sister showed no symptoms but a lack of glycogen was identified through muscle biopsy. The syndrome is caused by homozygous missense mutations in the gene encoding muscle glycogen synthase. |
Finding site |
True |
Myocardium structure |
Inferred relationship |
Some |
1 |
Microcephaly-cardiomyopathy syndrome is characterized by severe intellectual deficit, microcephaly and dilated cardiomyopathy. Hand and foot anomalies have also been reported. The syndrome has been described in three individuals. Transmission is autosomal recessive. |
Finding site |
True |
Myocardium structure |
Inferred relationship |
Some |
1 |
Dilated cardiomyopathy due to electrolyte imbalance (disorder) |
Finding site |
True |
Myocardium structure |
Inferred relationship |
Some |
1 |
Dilated cardiomyopathy due to infiltration |
Finding site |
False |
Myocardium structure |
Inferred relationship |
Some |
2 |
Dilated cardiomyopathy due to haemochromatosis |
Finding site |
False |
Myocardium structure |
Inferred relationship |
Some |
3 |
Dilated cardiomyopathy due to amyloidosis (disorder) |
Finding site |
True |
Myocardium structure |
Inferred relationship |
Some |
3 |
Dilated cardiomyopathy due to parasitic myocarditis |
Finding site |
True |
Myocardium structure |
Inferred relationship |
Some |
1 |
Dilated cardiomyopathy due to haemochromatosis |
Finding site |
True |
Myocardium structure |
Inferred relationship |
Some |
5 |
Dilated cardiomyopathy due to amyloidosis (disorder) |
Finding site |
True |
Myocardium structure |
Inferred relationship |
Some |
5 |
Dilated cardiomyopathy due to infiltration |
Finding site |
True |
Myocardium structure |
Inferred relationship |
Some |
4 |
Postoperative acute myocardial infarction |
Finding site |
True |
Myocardium structure |
Inferred relationship |
Some |
1 |
A rare mitochondrial disease characterized by early onset of hypertrophic cardiomyopathy and variable neurologic symptoms including global developmental delay, hypotonia, intellectual disability, visual impairment, and seizures. Lactic acidosis is present in all patients. Muscle biopsy usually shows decreased activity of mitochondrial complexes I and IV. Brain imaging may reveal variable abnormal signal intensities in the thalamus, basal ganglia, and/or brain stem. |
Finding site |
True |
Myocardium structure |
Inferred relationship |
Some |
3 |
A rare, inherited, epidermolysis bullosa characterized by aplasia cutis congenita on the extremities, leaving behind hypopigmentation and atrophy in a whirled pattern. Generalized blistering persists during childhood and heals with cutaneous and follicular atrophy, linear and stellate scars, and hypopigmentation. Skin fragility decreases with adulthood. Adult patients exhibit dyspigmentation and atrophy of the skin, scars, follicular atrophoderma, sparse body hair, progressive diffuse alopecia of the scalp, diffuse palmoplantar keratoderma, and nail changes. Dilated cardiomyopathy with heart failure complicates the disease course in young adulthood or later and may have lethal outcome. Ultra-structurally, intraepidermal splitting appears at the level of the basal keratinocytes, above the hemidesmosomes. |
Finding site |
True |
Myocardium structure |
Inferred relationship |
Some |
1 |
Implantation of blood vessels into myocardium |
Procedure site - Indirect (attribute) |
True |
Myocardium structure |
Inferred relationship |
Some |
2 |