75359005: Timolol maleate (substance)

SNOMED CT Concept\Substance\...

\Substance categorized by disposition\Substance with receptor antagonist mechanism of action (substance)\Substance with adrenergic receptor antagonist mechanism of action (substance)\Substance with beta adrenergic receptor antagonist mechanism of action (substance)\Timolol maleate

\A grouper concept for substances that are used in medicinal products for medical treatment, and also psychoactive substances that have few or no legitimate medical uses or that are not legally available to the person using them.\Autonomic agent (substance)\Substance with beta adrenergic receptor antagonist mechanism of action (substance)\Timolol maleate
\A grouper concept for substances that are used in medicinal products for medical treatment, and also psychoactive substances that have few or no legitimate medical uses or that are not legally available to the person using them.\Cardiovascular agent (substance)\Hypotensive agent (substance)\Substance with beta adrenergic receptor antagonist mechanism of action (substance)\Timolol maleate

\Substance categorised by structure\Chemical\Chemical categorized by structure (substance)\...

\Nitrogen and/or nitrogen compound (substance)\Nitrogen compound\Organic nitrogen compound\Amine and/or amine derivative\Amine\Amino alcohol\Alkanolamine (substance)\Propanolamine (substance)\Timolol maleate

\Organic compound\Organic nitrogen compound\Amine and/or amine derivative\Amine\Amino alcohol\Alkanolamine (substance)\Propanolamine (substance)\Timolol maleate
\Organic compound\Substance with alcohol structure (substance)\Amino alcohol\Alkanolamine (substance)\Propanolamine (substance)\Timolol maleate

Status: current, Not sufficiently defined by necessary conditions definition status (core metadata concept). Date: 31-Jan 2002. Module: SNOMED CT core

Descriptions:

Id Description Lang Type Status Case? Module

125158014 Timolol maleate en Synonym (core metadata concept) Active Entire term case insensitive (core metadata concept) SNOMED CT core

815959014 Timolol maleate (substance) en Fully specified name Active Entire term case insensitive (core metadata concept) SNOMED CT core

29011000188113 timolol maléate fr Synonym (core metadata concept) Active Entire term case insensitive (core metadata concept) SNOMED CT Switzerland NRC maintained Module

845961000172110 maléate de timolol fr Synonym (core metadata concept) Active Entire term case insensitive (core metadata concept) SNOMED CT Switzerland NRC maintained Module

Expanded Value Set

Outbound Relationships	Type	Target	Active	Characteristic	Refinability	Group	Values
Timolol maleate	Is a	Product containing timolol (medicinal product)	false	Inferred relationship	Some
Timolol maleate	Is a	Timolol (substance)	false	Inferred relationship	Some
Timolol maleate	This attribute specifies the behavior that a substance will exhibit or participate in, given the appropriate context.	Beta adrenergic receptor antagonist (disposition)	true	Inferred relationship	Some
Timolol maleate	This attribute indicates that the concept is a structural modification of another concept, and that the substance's intrinsic physicochemical properties remain unchanged.	Timolol (substance)	true	Inferred relationship	Some
Timolol maleate	Is a	Propanolamine (substance)	true	Inferred relationship	Some
Timolol maleate	Is a	Non-selective beta-blocking agent	false	Inferred relationship	Some
Timolol maleate	Is a	Substance with beta adrenergic receptor antagonist mechanism of action (substance)	true	Inferred relationship	Some

Inbound Relationships	Type	Active	Source	Characteristic	Refinability	Group
Timolol maleate 10 mg oral tablet	Is a	False	Timolol maleate	Inferred relationship	Some
Timolol maleate [b-blocker]	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Timolol maleate	Inferred relationship	Some
Timolol maleate 10 mg oral tablet	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Timolol maleate	Inferred relationship	Some
Timolol maleate [eye]	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Timolol maleate	Inferred relationship	Some
Timolol maleate 0.5% gel	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Timolol maleate	Inferred relationship	Some
Timolol maleate 0.25% gel	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Timolol maleate	Inferred relationship	Some
Timolol maleate 5 mg oral tablet	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Timolol maleate	Inferred relationship	Some
Timolol maleate 20 mg oral tablet	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Timolol maleate	Inferred relationship	Some
Timolol maleate 0.25% ophthalmic solution	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Timolol maleate	Inferred relationship	Some
Timolol maleate 0.5% ophthalmic solution	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Timolol maleate	Inferred relationship	Some
Product containing precisely amiloride hydrochloride 2.5 milligram and hydrochlorothiazide 25 milligram and timolol maleate 10 milligram/1 each conventional release oral tablet (clinical drug)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Timolol maleate	Inferred relationship	Some
Bendroflumethiazide 2.5 mg and timolol maleate 10 mg oral tablet	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Timolol maleate	Inferred relationship	Some
Hydrochlorothiazide + timolol maleate 25mg/10mg tablet	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Timolol maleate	Inferred relationship	Some
Product containing hydrochlorothiazide and timolol maleate	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Timolol maleate	Inferred relationship	Some
Hydrochlorothiazide 25 mg and timolol maleate 10 mg oral tablet	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Timolol maleate	Inferred relationship	Some
Product containing amiloride and hydrochlorothiazide and timolol maleate	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Timolol maleate	Inferred relationship	Some
Dorzolamide (as dorzolamide hydrochloride) 20 mg/mL and timolol (as timolol maleate) 5 mg/mL eye drops	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Timolol maleate	Inferred relationship	Some
Timolol maleate 10 mg oral tablet	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Timolol maleate	Inferred relationship	Some	1
Timolol maleate 10 mg oral tablet	This attribute represents an ingredient that is the part of the active ingredient that the strength of a given product is based upon.	True	Timolol maleate	Inferred relationship	Some	1
Product containing precisely amiloride hydrochloride 2.5 milligram and hydrochlorothiazide 25 milligram and timolol maleate 10 milligram/1 each conventional release oral tablet (clinical drug)	This attribute represents an ingredient that is the part of the active ingredient that the strength of a given product is based upon.	False	Timolol maleate	Inferred relationship	Some	2
Bendroflumethiazide 2.5 mg and timolol maleate 10 mg oral tablet	This attribute represents an ingredient that is the part of the active ingredient that the strength of a given product is based upon.	False	Timolol maleate	Inferred relationship	Some	1
Timolol maleate 5 mg oral tablet	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Timolol maleate	Inferred relationship	Some	1
Timolol maleate 5 mg oral tablet	This attribute represents an ingredient that is the part of the active ingredient that the strength of a given product is based upon.	True	Timolol maleate	Inferred relationship	Some	1
Timolol maleate 20 mg oral tablet	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Timolol maleate	Inferred relationship	Some	1
Timolol maleate 20 mg oral tablet	This attribute represents an ingredient that is the part of the active ingredient that the strength of a given product is based upon.	True	Timolol maleate	Inferred relationship	Some	1
Hydrochlorothiazide 25 mg and timolol maleate 10 mg oral tablet	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Timolol maleate	Inferred relationship	Some	1
Hydrochlorothiazide 25 mg and timolol maleate 10 mg oral tablet	This attribute represents an ingredient that is the part of the active ingredient that the strength of a given product is based upon.	False	Timolol maleate	Inferred relationship	Some	1
Bendroflumethiazide 2.5 mg and timolol maleate 10 mg oral tablet	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Timolol maleate	Inferred relationship	Some	2
Bendroflumethiazide 2.5 mg and timolol maleate 10 mg oral tablet	This attribute represents an ingredient that is the part of the active ingredient that the strength of a given product is based upon.	True	Timolol maleate	Inferred relationship	Some	2
Product containing precisely amiloride hydrochloride 2.5 milligram and hydrochlorothiazide 25 milligram and timolol maleate 10 milligram/1 each conventional release oral tablet (clinical drug)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Timolol maleate	Inferred relationship	Some	1
Product containing precisely amiloride hydrochloride 2.5 milligram and hydrochlorothiazide 25 milligram and timolol maleate 10 milligram/1 each conventional release oral tablet (clinical drug)	This attribute represents an ingredient that is the part of the active ingredient that the strength of a given product is based upon.	False	Timolol maleate	Inferred relationship	Some	1
Timolol maleate 10 mg oral tablet	The most specific description of a substance present in the manufactured dose form, before any dilution or transformation. It includes modifiers, such as salts, esters, polymers (e.g. pegylation), and/or solvates (including waters of hydration).	True	Timolol maleate	Inferred relationship	Some	1
Timolol maleate 20 mg oral tablet	The most specific description of a substance present in the manufactured dose form, before any dilution or transformation. It includes modifiers, such as salts, esters, polymers (e.g. pegylation), and/or solvates (including waters of hydration).	True	Timolol maleate	Inferred relationship	Some	1
Timolol maleate 5 mg oral tablet	The most specific description of a substance present in the manufactured dose form, before any dilution or transformation. It includes modifiers, such as salts, esters, polymers (e.g. pegylation), and/or solvates (including waters of hydration).	True	Timolol maleate	Inferred relationship	Some	1
Bendroflumethiazide 2.5 mg and timolol maleate 10 mg oral tablet	The most specific description of a substance present in the manufactured dose form, before any dilution or transformation. It includes modifiers, such as salts, esters, polymers (e.g. pegylation), and/or solvates (including waters of hydration).	False	Timolol maleate	Inferred relationship	Some	1
Hydrochlorothiazide 25 mg and timolol maleate 10 mg oral tablet	The most specific description of a substance present in the manufactured dose form, before any dilution or transformation. It includes modifiers, such as salts, esters, polymers (e.g. pegylation), and/or solvates (including waters of hydration).	False	Timolol maleate	Inferred relationship	Some	1
Product containing precisely amiloride hydrochloride 2.5 milligram and hydrochlorothiazide 25 milligram and timolol maleate 10 milligram/1 each conventional release oral tablet (clinical drug)	The most specific description of a substance present in the manufactured dose form, before any dilution or transformation. It includes modifiers, such as salts, esters, polymers (e.g. pegylation), and/or solvates (including waters of hydration).	False	Timolol maleate	Inferred relationship	Some	2
Timolol (as timolol maleate) 1 mg/mL eye gel	The most specific description of a substance present in the manufactured dose form, before any dilution or transformation. It includes modifiers, such as salts, esters, polymers (e.g. pegylation), and/or solvates (including waters of hydration).	True	Timolol maleate	Inferred relationship	Some	1
Timolol (as timolol maleate) 2.5 mg/mL eye gel	The most specific description of a substance present in the manufactured dose form, before any dilution or transformation. It includes modifiers, such as salts, esters, polymers (e.g. pegylation), and/or solvates (including waters of hydration).	True	Timolol maleate	Inferred relationship	Some	1
Product containing precisely timolol (as timolol maleate) 5 milligram/1 milliliter conventional release eye gel (clinical drug)	The most specific description of a substance present in the manufactured dose form, before any dilution or transformation. It includes modifiers, such as salts, esters, polymers (e.g. pegylation), and/or solvates (including waters of hydration).	True	Timolol maleate	Inferred relationship	Some	1
Timolol (as timolol maleate) 2.5 mg/mL eye drops	The most specific description of a substance present in the manufactured dose form, before any dilution or transformation. It includes modifiers, such as salts, esters, polymers (e.g. pegylation), and/or solvates (including waters of hydration).	True	Timolol maleate	Inferred relationship	Some	1
Product containing precisely latanoprost 50 microgram/1 milliliter and timolol (as timolol maleate) 5 milligram/1 milliliter conventional release eye drops (clinical drug)	The most specific description of a substance present in the manufactured dose form, before any dilution or transformation. It includes modifiers, such as salts, esters, polymers (e.g. pegylation), and/or solvates (including waters of hydration).	True	Timolol maleate	Inferred relationship	Some	1
Product containing precisely timolol (as timolol maleate) 5 milligram/1 milliliter conventional release eye drops (clinical drug)	The most specific description of a substance present in the manufactured dose form, before any dilution or transformation. It includes modifiers, such as salts, esters, polymers (e.g. pegylation), and/or solvates (including waters of hydration).	True	Timolol maleate	Inferred relationship	Some	1
Dorzolamide (as dorzolamide hydrochloride) 20 mg/mL and timolol (as timolol maleate) 5 mg/mL eye drops	The most specific description of a substance present in the manufactured dose form, before any dilution or transformation. It includes modifiers, such as salts, esters, polymers (e.g. pegylation), and/or solvates (including waters of hydration).	True	Timolol maleate	Inferred relationship	Some	1
Product containing precisely timolol (as timolol maleate) 2.5 milligram/1 milliliter conventional release eye solution (clinical drug)	The most specific description of a substance present in the manufactured dose form, before any dilution or transformation. It includes modifiers, such as salts, esters, polymers (e.g. pegylation), and/or solvates (including waters of hydration).	False	Timolol maleate	Inferred relationship	Some	1
Product containing precisely timolol (as timolol maleate) 5 milligram/1 milliliter conventional release eye solution (clinical drug)	The most specific description of a substance present in the manufactured dose form, before any dilution or transformation. It includes modifiers, such as salts, esters, polymers (e.g. pegylation), and/or solvates (including waters of hydration).	False	Timolol maleate	Inferred relationship	Some	1
Product containing precisely amiloride hydrochloride 2.5 milligram and hydrochlorothiazide 25 milligram and timolol maleate 10 milligram/1 each conventional release oral tablet (clinical drug)	The most specific description of a substance present in the manufactured dose form, before any dilution or transformation. It includes modifiers, such as salts, esters, polymers (e.g. pegylation), and/or solvates (including waters of hydration).	True	Timolol maleate	Inferred relationship	Some	3
Product containing precisely amiloride hydrochloride 2.5 milligram and hydrochlorothiazide 25 milligram and timolol maleate 10 milligram/1 each conventional release oral tablet (clinical drug)	This attribute represents an ingredient that is the part of the active ingredient that the strength of a given product is based upon.	True	Timolol maleate	Inferred relationship	Some	3
Bendroflumethiazide 2.5 mg and timolol maleate 10 mg oral tablet	The most specific description of a substance present in the manufactured dose form, before any dilution or transformation. It includes modifiers, such as salts, esters, polymers (e.g. pegylation), and/or solvates (including waters of hydration).	True	Timolol maleate	Inferred relationship	Some	2
Hydrochlorothiazide 25 mg and timolol maleate 10 mg oral tablet	This attribute represents an ingredient that is the part of the active ingredient that the strength of a given product is based upon.	True	Timolol maleate	Inferred relationship	Some	2
Hydrochlorothiazide 25 mg and timolol maleate 10 mg oral tablet	The most specific description of a substance present in the manufactured dose form, before any dilution or transformation. It includes modifiers, such as salts, esters, polymers (e.g. pegylation), and/or solvates (including waters of hydration).	True	Timolol maleate	Inferred relationship	Some	2
Product containing precisely timolol (as timolol maleate) 5 milligram/1 milliliter and travoprost 40 microgram/1 milliliter conventional release eye drops (clinical drug)	The most specific description of a substance present in the manufactured dose form, before any dilution or transformation. It includes modifiers, such as salts, esters, polymers (e.g. pegylation), and/or solvates (including waters of hydration).	True	Timolol maleate	Inferred relationship	Some	2
Bimatoprost 300 microgram/mL and timolol (as timolol maleate) 5 mg/mL eye drops	The most specific description of a substance present in the manufactured dose form, before any dilution or transformation. It includes modifiers, such as salts, esters, polymers (e.g. pegylation), and/or solvates (including waters of hydration).	True	Timolol maleate	Inferred relationship	Some	2
Brinzolamide 10 mg/mL and timolol (as timolol maleate) 5 mg/mL eye drops suspension	The most specific description of a substance present in the manufactured dose form, before any dilution or transformation. It includes modifiers, such as salts, esters, polymers (e.g. pegylation), and/or solvates (including waters of hydration).	True	Timolol maleate	Inferred relationship	Some	1
Product containing precisely tafluprost 15 microgram/1 milliliter and timolol (as timolol maleate) 5 milligram/1 milliliter conventional release solution for eye drops (clinical drug)	The most specific description of a substance present in the manufactured dose form, before any dilution or transformation. It includes modifiers, such as salts, esters, polymers (e.g. pegylation), and/or solvates (including waters of hydration).	True	Timolol maleate	Inferred relationship	Some	1

This concept is not in any reference sets

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Id	Description	Lang	Type	Status	Case?	Module
125158014	Timolol maleate	en	Synonym (core metadata concept)	Active	Entire term case insensitive (core metadata concept)	SNOMED CT core
815959014	Timolol maleate (substance)	en	Fully specified name	Active	Entire term case insensitive (core metadata concept)	SNOMED CT core
29011000188113	timolol maléate	fr	Synonym (core metadata concept)	Active	Entire term case insensitive (core metadata concept)	SNOMED CT Switzerland NRC maintained Module
845961000172110	maléate de timolol	fr	Synonym (core metadata concept)	Active	Entire term case insensitive (core metadata concept)	SNOMED CT Switzerland NRC maintained Module