75777003: Cytokine (substance)

SNOMED CT Concept\Substance\...

\Substance categorized by disposition\Immunomodulator\Mediator of immune response and inflammation (substance)\Mediator of immune response\Cytokine

\Substance categorised by structure\Chemical\Chemical categorized by structure (substance)\...

\Nitrogen and/or nitrogen compound (substance)\Nitrogen compound\Organic nitrogen compound\Amide and/or amide derivative (substance)\Substituted amide (substance)\Polypeptide\Protein\Glycoprotein\Cytokine

\Organic compound\Organic nitrogen compound\Amide and/or amide derivative (substance)\Substituted amide (substance)\Polypeptide\Protein\Glycoprotein\Cytokine

\Biological substance\Protein and/or protein derivative\Protein\Glycoprotein\Cytokine
\Biological substance\Immunologic substance\Mediator of immune response and inflammation (substance)\Mediator of immune response\Cytokine
\Biological substance\Polypeptide\Protein\Glycoprotein\Cytokine

Status: current, Not sufficiently defined by necessary conditions definition status (core metadata concept). Date: 31-Jan 2002. Module: SNOMED CT core

Descriptions:

Id Description Lang Type Status Case? Module

125852012 Cytokine en Synonym (core metadata concept) Active Entire term case insensitive (core metadata concept) SNOMED CT core

816424012 Cytokine (substance) en Fully specified name Active Entire term case insensitive (core metadata concept) SNOMED CT core

7109781000241114 cytokine fr Synonym (core metadata concept) Active Entire term case insensitive (core metadata concept) SNOMED CT Switzerland NRC maintained Module

Expanded Value Set

Outbound Relationships	Type	Target	Active	Characteristic	Refinability	Group	Values
Cytokine	Is a	analyte immunologique	false	Inferred relationship	Some
Cytokine	Is a	Mediator of immune response	true	Inferred relationship	Some
Cytokine	Is a	Glycoprotein	true	Inferred relationship	Some
Cytokine	This attribute specifies the behavior that a substance will exhibit or participate in, given the appropriate context.	A substance that modifies the immune response or the functioning of the immune system.	true	Inferred relationship	Some

Inbound Relationships	Type	Active	Source	Characteristic	Refinability	Group
IL-2 assay	Has measured component (attribute)	False	Cytokine	Inferred relationship	Some
IL-6 assay	Has measured component (attribute)	False	Cytokine	Inferred relationship	Some
IL-7 assay	Has measured component (attribute)	False	Cytokine	Inferred relationship	Some
Mononuclear cell function assay	Has measured component (attribute)	False	Cytokine	Inferred relationship	Some
IL-3 assay	Has measured component (attribute)	False	Cytokine	Inferred relationship	Some
Cytokine assay	Has measured component (attribute)	False	Cytokine	Inferred relationship	Some
Interferon gamma assay	Has measured component (attribute)	False	Cytokine	Inferred relationship	Some
Intracellular free calcium assay	Has measured component (attribute)	False	Cytokine	Inferred relationship	Some
TNF, Beta assay	Has measured component (attribute)	False	Cytokine	Inferred relationship	Some
Interleukin-8 assay (procedure)	Has measured component (attribute)	False	Cytokine	Inferred relationship	Some
Protein kinase C activity assay	Has measured component (attribute)	False	Cytokine	Inferred relationship	Some
Interferon alpha assay	Has measured component (attribute)	False	Cytokine	Inferred relationship	Some
Lymphokine assay	Has measured component (attribute)	False	Cytokine	Inferred relationship	Some
Interferon assay	Has measured component (attribute)	False	Cytokine	Inferred relationship	Some
Interferon beta assay	Has measured component (attribute)	False	Cytokine	Inferred relationship	Some
IL-4 assay	Has measured component (attribute)	False	Cytokine	Inferred relationship	Some
IL-5 assay	Has measured component (attribute)	False	Cytokine	Inferred relationship	Some
Tumor necrosis factor assay	Has measured component (attribute)	False	Cytokine	Inferred relationship	Some
IL-2 assay	Component	False	Cytokine	Inferred relationship	Some
IL-6 assay	Component	False	Cytokine	Inferred relationship	Some
IL-7 assay	Component	False	Cytokine	Inferred relationship	Some
Mononuclear cell function assay	Component	False	Cytokine	Inferred relationship	Some	2
IL-3 assay	Component	False	Cytokine	Inferred relationship	Some
Cytokine assay	Component	True	Cytokine	Inferred relationship	Some	1
Interferon gamma assay	Component	False	Cytokine	Inferred relationship	Some
Intracellular free calcium assay	Component	False	Cytokine	Inferred relationship	Some	2
TNF, Beta assay	Component	False	Cytokine	Inferred relationship	Some
Interleukin-8 assay (procedure)	Component	False	Cytokine	Inferred relationship	Some
Protein kinase C activity assay	Component	False	Cytokine	Inferred relationship	Some	3
Interferon alpha assay	Component	False	Cytokine	Inferred relationship	Some
Lymphokine assay	Component	False	Cytokine	Inferred relationship	Some	3
Interferon assay	Component	False	Cytokine	Inferred relationship	Some
Interferon beta assay	Component	False	Cytokine	Inferred relationship	Some
IL-4 assay	Component	False	Cytokine	Inferred relationship	Some
IL-5 assay	Component	False	Cytokine	Inferred relationship	Some
Tumor necrosis factor assay	Component	False	Cytokine	Inferred relationship	Some
Product containing interferon gamma-1b (medicinal product)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Cytokine	Inferred relationship	Some
Product containing interferon beta-1a (medicinal product)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Cytokine	Inferred relationship	Some
Product containing interferon beta-1b (medicinal product)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Cytokine	Inferred relationship	Some
Product containing interferon alfa-2a (medicinal product)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Cytokine	Inferred relationship	Some
Product containing interferon alfa-2b (medicinal product)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Cytokine	Inferred relationship	Some
Product containing cytokine (product)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Cytokine	Inferred relationship	Some	1
Product containing aldesleukin (medicinal product)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Cytokine	Inferred relationship	Some
Product containing peginterferon alfa-2b (medicinal product)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Cytokine	Inferred relationship	Some
Interferon alfa-containing product	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Cytokine	Inferred relationship	Some
Interferon beta-containing product	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Cytokine	Inferred relationship	Some
Product containing interferon gamma (medicinal product)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Cytokine	Inferred relationship	Some
Human interferon gamma-1b 200 micrograms/mL injection solution 0.5mL vial	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Cytokine	Inferred relationship	Some
Interferon alfa-2b 10million iu powder and solvent for injection solution vial	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Cytokine	Inferred relationship	Some
Interferon alfa-2b 5million iu powder and solvent for injection solution vial	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Cytokine	Inferred relationship	Some
Interferon alfa-2b 3million iu powder and solvent for injection solution vial	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Cytokine	Inferred relationship	Some
Interferon alfa-2b 1million iu powder and solvent for injection solution vial	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Cytokine	Inferred relationship	Some
Interferon alfa-2b 6million iu/mL injection solution 3mL vial	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Cytokine	Inferred relationship	Some
Interferon alfa-2a 18million iu/mL injection solution 1mL vial	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Cytokine	Inferred relationship	Some
Interferon beta-1b 8million iu powder and solvent for injection solution vial	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Cytokine	Inferred relationship	Some
Interferons 1million iu injection (pdr for recon)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Cytokine	Inferred relationship	Some
Interferons 4.5million iu injection	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Cytokine	Inferred relationship	Some
Interferons 5million units injection (pdr for recon)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Cytokine	Inferred relationship	Some
Interferons 10million iu injection (pdr for recon)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Cytokine	Inferred relationship	Some
Interferons 30million iu injection (pdr for recon)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Cytokine	Inferred relationship	Some
Interferons 3million iu injection (pdr for recon)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Cytokine	Inferred relationship	Some
Interferons 9million iu injection (pdr for recon)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Cytokine	Inferred relationship	Some
Interferons 18million iu injection (pdr for recon)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Cytokine	Inferred relationship	Some
Interferons 3million iu/1mL solution for injection	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Cytokine	Inferred relationship	Some
Interferons 10million iu/1mL solution for injection	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Cytokine	Inferred relationship	Some
Interferons (2)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Cytokine	Inferred relationship	Some
Interferon alfa-2a 6million iu/mL injection solution 0.5mL prefilled syringe	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Cytokine	Inferred relationship	Some
Interferon alfa-2a 9million iu/mL injection solution 0.5mL prefilled syringe	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Cytokine	Inferred relationship	Some
Interferon alfa-2a 12million iu/mL injection solution 0.5mL prefilled syringe	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Cytokine	Inferred relationship	Some
Interferon alfa-2a 18million iu/mL injection solution 0.5mL prefilled syringe	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Cytokine	Inferred relationship	Some
Interferon beta-1a 6million iu powder and solvent for injection solution vial	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Cytokine	Inferred relationship	Some
Interferon alfa-2b 15million iu/1mL prefilled pen	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Cytokine	Inferred relationship	Some
Interferon alfa-2b 25million iu/1mL prefilled pen	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Cytokine	Inferred relationship	Some
Interferon alfa-2b 50million iu/1mL prefilled pen	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Cytokine	Inferred relationship	Some
Interferon alfa-2b 10million iu/mL injection solution 2.5mL vial	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Cytokine	Inferred relationship	Some
Interferon beta-1a 12million iu/mL injection solution 0.5mL prefilled syringe	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Cytokine	Inferred relationship	Some
Interferon beta-1a 24million iu/mL injection solution 0.5mL prefilled syringe	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Cytokine	Inferred relationship	Some
Interferon alfa-2a 18million iu/0.6mL injection solution cartridge	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Cytokine	Inferred relationship	Some
Peginterferon alfa-2b 50micrograms powder and solvent for injection solution vial	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Cytokine	Inferred relationship	Some
Peginterferon alfa-2b 80micrograms powder and solvent for injection solution vial	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Cytokine	Inferred relationship	Some
Peginterferon alfa-2b 100micrograms powder and solvent for injection solution vial	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Cytokine	Inferred relationship	Some
Peginterferon alfa-2b 150micrograms powder and solvent for injection solution vial	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Cytokine	Inferred relationship	Some
Peginterferon alfa-2b 120micrograms powder and solvent for injection solution vial	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Cytokine	Inferred relationship	Some
Product containing interferon alfa-n1 (medicinal product)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Cytokine	Inferred relationship	Some
Aldesleukin 18megaunits powder for injection solution vial	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Cytokine	Inferred relationship	Some
Interferon alfa-2b 30000000iu solution	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Cytokine	Inferred relationship	Some
Interferon alfa-2b 60million/iu solution	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Cytokine	Inferred relationship	Some
Interferon alfa-2b 150mcg powder	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Cytokine	Inferred relationship	Some
Interferon alfa-2b 300mcg powder	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Cytokine	Inferred relationship	Some
Interferon alfa-2b 120mcg powder	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Cytokine	Inferred relationship	Some
Interferon alfa-2b 600mcg powder	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Cytokine	Inferred relationship	Some
Interferon alfa-2b 100.000mcg powder	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Cytokine	Inferred relationship	Some
Interferon alfa-2b 50mcg powder	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Cytokine	Inferred relationship	Some
Interferon alfa-n3 human leu 5000000unt/mL injection	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Cytokine	Inferred relationship	Some
Interferon alfa-2a 18000000iu/3mL injection	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Cytokine	Inferred relationship	Some
Interferon alfa-2a 36000000iu/mL injection	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Cytokine	Inferred relationship	Some
Interferon alfa-2a 3miu injection	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Cytokine	Inferred relationship	Some
Interferon alfa-2a 6miu injection	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Cytokine	Inferred relationship	Some
Interferon alfa-2a 9miu injection	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Cytokine	Inferred relationship	Some
Interferon alfacon-130mcg/mL injection solution 0.3mL cartridge	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Cytokine	Inferred relationship	Some
Interferon beta-1b 100mcg injection solution	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Cytokine	Inferred relationship	Some

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Id	Description	Lang	Type	Status	Case?	Module
125852012	Cytokine	en	Synonym (core metadata concept)	Active	Entire term case insensitive (core metadata concept)	SNOMED CT core
816424012	Cytokine (substance)	en	Fully specified name	Active	Entire term case insensitive (core metadata concept)	SNOMED CT core
7109781000241114	cytokine	fr	Synonym (core metadata concept)	Active	Entire term case insensitive (core metadata concept)	SNOMED CT Switzerland NRC maintained Module