771596001: Tezacaftor (substance)

SNOMED CT Concept\Substance\...

\Substance categorized by disposition\Substance with cystic fibrosis transmembrane conductance regulator potentiator mechanism of action (substance)\Tezacaftor (substance)

\Substance categorised by structure\Chemical\Chemical categorized by structure (substance)\Organic compound\Organic cyclic compound\Heterocyclic compound\Dioxole (substance)\Tezacaftor (substance)

Status: current, Not sufficiently defined by necessary conditions definition status (core metadata concept). Date: 31-Jan 2019. Module: SNOMED CT core

Descriptions:

Id Description Lang Type Status Case? Module

3706939018 Tezacaftor (substance) en Fully specified name Active Entire term case insensitive (core metadata concept) SNOMED CT core

3706940016 Tezacaftor en Synonym (core metadata concept) Active Entire term case insensitive (core metadata concept) SNOMED CT core

5521941000241117 tezacaftor fr Synonym (core metadata concept) Active Entire term case insensitive (core metadata concept) SNOMED CT Switzerland NRC maintained Module

Expanded Value Set

Outbound Relationships	Type	Target	Active	Characteristic	Refinability	Group	Values
Tezacaftor (substance)	Is a	Dioxole (substance)	true	Inferred relationship	Some
Tezacaftor (substance)	This attribute specifies the behavior that a substance will exhibit or participate in, given the appropriate context.	Cystic fibrosis transmembrane conductance regulator potentiator (disposition)	true	Inferred relationship	Some
Tezacaftor (substance)	Is a	Substance with cystic fibrosis transmembrane conductance regulator potentiator mechanism of action (substance)	true	Inferred relationship	Some

Inbound Relationships	Type	Active	Source	Characteristic	Refinability	Group
Product containing ivacaftor and tezacaftor (medicinal product)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Tezacaftor (substance)	Inferred relationship	Some	2
Ivacaftor- and tezacaftor-containing product in oral dose form	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Tezacaftor (substance)	Inferred relationship	Some	2
Product containing only ivacaftor and tezacaftor (medicinal product)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Tezacaftor (substance)	Inferred relationship	Some	2
Ivacaftor and tezacaftor only product in oral dose form	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Tezacaftor (substance)	Inferred relationship	Some	2
Elexacaftor- and ivacaftor- and tezacaftor-containing product	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Tezacaftor (substance)	Inferred relationship	Some	2
Product containing elexacaftor and ivacaftor and tezacaftor in oral dose form (medicinal product form)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Tezacaftor (substance)	Inferred relationship	Some	2
Elexacaftor and ivacaftor and tezacaftor only product	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Tezacaftor (substance)	Inferred relationship	Some	2
Product containing only elexacaftor and ivacaftor and tezacaftor in oral dose form (medicinal product form)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Tezacaftor (substance)	Inferred relationship	Some	2
Elexacaftor 50 mg and ivacaftor 37.5 mg and tezacaftor 25 mg oral tablet	The most specific description of a substance present in the manufactured dose form, before any dilution or transformation. It includes modifiers, such as salts, esters, polymers (e.g. pegylation), and/or solvates (including waters of hydration).	True	Tezacaftor (substance)	Inferred relationship	Some	2
Elexacaftor 50 mg and ivacaftor 37.5 mg and tezacaftor 25 mg oral tablet	This attribute represents an ingredient that is the part of the active ingredient that the strength of a given product is based upon.	True	Tezacaftor (substance)	Inferred relationship	Some	2
Elexacaftor 100 mg and ivacaftor 75 mg and tezacaftor 50 mg oral tablet	The most specific description of a substance present in the manufactured dose form, before any dilution or transformation. It includes modifiers, such as salts, esters, polymers (e.g. pegylation), and/or solvates (including waters of hydration).	True	Tezacaftor (substance)	Inferred relationship	Some	2
Elexacaftor 100 mg and ivacaftor 75 mg and tezacaftor 50 mg oral tablet	This attribute represents an ingredient that is the part of the active ingredient that the strength of a given product is based upon.	True	Tezacaftor (substance)	Inferred relationship	Some	2
Product containing precisely ivacaftor 150 milligram and tezacaftor 100 milligram/1 each conventional release oral tablet (clinical drug)	The most specific description of a substance present in the manufactured dose form, before any dilution or transformation. It includes modifiers, such as salts, esters, polymers (e.g. pegylation), and/or solvates (including waters of hydration).	True	Tezacaftor (substance)	Inferred relationship	Some	2
Product containing precisely ivacaftor 150 milligram and tezacaftor 100 milligram/1 each conventional release oral tablet (clinical drug)	This attribute represents an ingredient that is the part of the active ingredient that the strength of a given product is based upon.	True	Tezacaftor (substance)	Inferred relationship	Some	2
Product containing precisely ivacaftor 75 milligram and tezacaftor 50 milligram/1 each conventional release oral tablet (clinical drug)	The most specific description of a substance present in the manufactured dose form, before any dilution or transformation. It includes modifiers, such as salts, esters, polymers (e.g. pegylation), and/or solvates (including waters of hydration).	True	Tezacaftor (substance)	Inferred relationship	Some	2
Product containing precisely ivacaftor 75 milligram and tezacaftor 50 milligram/1 each conventional release oral tablet (clinical drug)	This attribute represents an ingredient that is the part of the active ingredient that the strength of a given product is based upon.	True	Tezacaftor (substance)	Inferred relationship	Some	2

Reference Sets