781492009: Dacomitinib (substance)

SNOMED CT Concept\Substance\...

\Substance categorized by disposition\Substance with effector mechanism of action (substance)\Enzyme inhibitor\Transferase inhibitor\Phosphotransferase inhibitor\Protein kinase inhibitor\Protein-tyrosine kinase inhibitor\Dacomitinib

\A grouper concept for substances that are used in medicinal products for medical treatment, and also psychoactive substances that have few or no legitimate medical uses or that are not legally available to the person using them.\Antineoplastic agent (substance)\Dacomitinib

\Substance categorised by structure\Chemical\Chemical categorized by structure (substance)\...

\Nitrogen and/or nitrogen compound (substance)\Nitrogen compound\Organic nitrogen compound\Pyridine and/or pyridine derivative\Piperidine\Dacomitinib

\Organic compound\Organic cyclic compound\Heterocyclic compound\Quinazoline (substance)\Dacomitinib
\Organic compound\Organic cyclic compound\Heterocyclic compound\Pyridine and/or pyridine derivative\Piperidine\Dacomitinib
\Organic compound\Organic nitrogen compound\Pyridine and/or pyridine derivative\Piperidine\Dacomitinib

Status: current, Not sufficiently defined by necessary conditions definition status (core metadata concept). Date: 31-Jan 2019. Module: SNOMED CT core

Descriptions:

Id Description Lang Type Status Case? Module

3747351018 Dacomitinib en Synonym (core metadata concept) Active Entire term case insensitive (core metadata concept) SNOMED CT core

3747352013 Dacomitinib (substance) en Fully specified name Active Entire term case insensitive (core metadata concept) SNOMED CT core

375011000195115 dacomitinib it Synonym (core metadata concept) Active Entire term case insensitive (core metadata concept) SNOMED CT Switzerland NRC maintained Module

1133721000241119 dacomitinib fr Synonym (core metadata concept) Active Entire term case insensitive (core metadata concept) SNOMED CT Switzerland NRC maintained Module

Expanded Value Set

Outbound Relationships	Type	Target	Active	Characteristic	Refinability	Group	Values
Dacomitinib	Is a	Quinazoline (substance)	true	Inferred relationship	Some
Dacomitinib	Is a	Piperidine	true	Inferred relationship	Some
Dacomitinib	Is a	Protein-tyrosine kinase inhibitor	true	Inferred relationship	Some
Dacomitinib	This attribute specifies the behavior that a substance will exhibit or participate in, given the appropriate context.	Protein-tyrosine kinase inhibitor (disposition)	true	Inferred relationship	Some
Dacomitinib	Is a	Enzyme inhibitor	false	Inferred relationship	Some
Dacomitinib	Is a	Antineoplastic agent (substance)	true	Inferred relationship	Some

Inbound Relationships	Type	Active	Source	Characteristic	Refinability	Group
Dacomitinib only product	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Dacomitinib	Inferred relationship	Some	1
Dacomitinib-containing product	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Dacomitinib	Inferred relationship	Some	1
Dacomitinib-containing product in oral dose form	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Dacomitinib	Inferred relationship	Some	1
Dacomitinib only product in oral dose form	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Dacomitinib	Inferred relationship	Some	1
Dacomitinib 15 mg oral tablet	The most specific description of a substance present in the manufactured dose form, before any dilution or transformation. It includes modifiers, such as salts, esters, polymers (e.g. pegylation), and/or solvates (including waters of hydration).	True	Dacomitinib	Inferred relationship	Some	1
Dacomitinib 15 mg oral tablet	This attribute represents an ingredient that is the part of the active ingredient that the strength of a given product is based upon.	True	Dacomitinib	Inferred relationship	Some	1
Dacomitinib monohydrate (substance)	This attribute indicates that the concept is a structural modification of another concept, and that the substance's intrinsic physicochemical properties remain unchanged.	True	Dacomitinib	Inferred relationship	Some
Dacomitinib 30 mg oral tablet	The most specific description of a substance present in the manufactured dose form, before any dilution or transformation. It includes modifiers, such as salts, esters, polymers (e.g. pegylation), and/or solvates (including waters of hydration).	True	Dacomitinib	Inferred relationship	Some	1
Dacomitinib 30 mg oral tablet	This attribute represents an ingredient that is the part of the active ingredient that the strength of a given product is based upon.	True	Dacomitinib	Inferred relationship	Some	1
Dacomitinib 45 mg oral tablet	The most specific description of a substance present in the manufactured dose form, before any dilution or transformation. It includes modifiers, such as salts, esters, polymers (e.g. pegylation), and/or solvates (including waters of hydration).	True	Dacomitinib	Inferred relationship	Some	1
Dacomitinib 45 mg oral tablet	This attribute represents an ingredient that is the part of the active ingredient that the strength of a given product is based upon.	True	Dacomitinib	Inferred relationship	Some	1
Dacomitinib anhydrous (substance)	This attribute indicates that the concept is a structural modification of another concept, and that the substance's intrinsic physicochemical properties remain unchanged.	True	Dacomitinib	Inferred relationship	Some

This concept is not in any reference sets