782976007: Lorlatinib (substance)

SNOMED CT Concept\Substance\...

\Substance categorized by disposition\Substance with effector mechanism of action (substance)\Enzyme inhibitor\Transferase inhibitor\Phosphotransferase inhibitor\Protein kinase inhibitor\Protein-tyrosine kinase inhibitor\Lorlatinib

\A grouper concept for substances that are used in medicinal products for medical treatment, and also psychoactive substances that have few or no legitimate medical uses or that are not legally available to the person using them.\Antineoplastic agent (substance)\Lorlatinib

\Substance categorised by structure\Chemical\Chemical categorized by structure (substance)\...

\Nitrogen and/or nitrogen compound (substance)\Nitrogen compound\Organic nitrogen compound\Amide and/or amide derivative (substance)\Amide\Lactam\Lorlatinib

\Organic compound\Organic cyclic compound\Heterocyclic compound\Lactam\Lorlatinib
\Organic compound\Organic nitrogen compound\Amide and/or amide derivative (substance)\Amide\Lactam\Lorlatinib

Status: current, Not sufficiently defined by necessary conditions definition status (core metadata concept). Date: 31-Jul 2019. Module: SNOMED CT core

Descriptions:

Id Description Lang Type Status Case? Module

3757029013 Lorlatinib en Synonym (core metadata concept) Active Entire term case insensitive (core metadata concept) SNOMED CT core

3757030015 Lorlatinib (substance) en Fully specified name Active Entire term case insensitive (core metadata concept) SNOMED CT core

368361000195118 lorlatinib it Synonym (core metadata concept) Active Entire term case insensitive (core metadata concept) SNOMED CT Switzerland NRC maintained Module

1135001000241111 lorlatinib fr Synonym (core metadata concept) Active Entire term case insensitive (core metadata concept) SNOMED CT Switzerland NRC maintained Module

Expanded Value Set

Outbound Relationships	Type	Target	Active	Characteristic	Refinability	Group	Values
Lorlatinib	Is a	Lactam	true	Inferred relationship	Some
Lorlatinib	This attribute specifies the behavior that a substance will exhibit or participate in, given the appropriate context.	Protein-tyrosine kinase inhibitor (disposition)	true	Inferred relationship	Some
Lorlatinib	Is a	Protein-tyrosine kinase inhibitor	true	Inferred relationship	Some
Lorlatinib	Is a	Enzyme inhibitor	false	Inferred relationship	Some
Lorlatinib	Is a	Antineoplastic agent (substance)	true	Inferred relationship	Some

Inbound Relationships	Type	Active	Source	Characteristic	Refinability	Group
Product containing only lorlatinib (medicinal product)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Lorlatinib	Inferred relationship	Some	1
Product containing lorlatinib in oral dose form (medicinal product form)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Lorlatinib	Inferred relationship	Some	1
Product containing lorlatinib (medicinal product)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Lorlatinib	Inferred relationship	Some	1
Lorlatinib only product in oral dose form	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Lorlatinib	Inferred relationship	Some	1
Product containing precisely lorlatinib 100 milligram/1 each conventional release oral tablet (clinical drug)	The most specific description of a substance present in the manufactured dose form, before any dilution or transformation. It includes modifiers, such as salts, esters, polymers (e.g. pegylation), and/or solvates (including waters of hydration).	True	Lorlatinib	Inferred relationship	Some	1
Product containing precisely lorlatinib 100 milligram/1 each conventional release oral tablet (clinical drug)	This attribute represents an ingredient that is the part of the active ingredient that the strength of a given product is based upon.	True	Lorlatinib	Inferred relationship	Some	1
Lorlatinib 25 mg oral tablet	This attribute represents an ingredient that is the part of the active ingredient that the strength of a given product is based upon.	True	Lorlatinib	Inferred relationship	Some	1
Lorlatinib 25 mg oral tablet	The most specific description of a substance present in the manufactured dose form, before any dilution or transformation. It includes modifiers, such as salts, esters, polymers (e.g. pegylation), and/or solvates (including waters of hydration).	True	Lorlatinib	Inferred relationship	Some	1

This concept is not in any reference sets