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786909001: High grade B-cell lymphoma with MYC and BCL2 and/or BCL6 rearrangements (morphologic abnormality)


Status: current, Not sufficiently defined by necessary conditions definition status (core metadata concept). Date: 31-Jul 2019. Module: SNOMED CT core

Descriptions:

Id Description Lang Type Status Case? Module
3773041018 High grade B-cell lymphoma with MYC and BCL2 and/or BCL6 rearrangements (morphologic abnormality) en Fully specified name Active Only initial character case insensitive (core metadata concept) SNOMED CT core
3773042013 High grade B-cell lymphoma with MYC and BCL2 and/or BCL6 rearrangements en Synonym (core metadata concept) Active Only initial character case insensitive (core metadata concept) SNOMED CT core


0 descendants.

Expanded Value Set


Outbound Relationships Type Target Active Characteristic Refinability Group Values
High grade B-cell lymphoma with MYC and BCL2 and/or BCL6 rearrangements (morphologic abnormality) Is a High grade B-cell lymphoma morphology true Inferred relationship Some
High grade B-cell lymphoma with MYC and BCL2 and/or BCL6 rearrangements (morphologic abnormality) Is a Diffuse large B cell malignant lymphoma (morphologic abnormality) true Inferred relationship Some

Inbound Relationships Type Active Source Characteristic Refinability Group
A rare aggressive B-cell non-Hodgkin lymphoma characterized by a rearrangement in MYC and BCL2 and/or BCL6 (so-called double-hit or triple-hit lymphoma). The category includes double-hit cases with features intermediate between diffuse large B-cell lymphoma (DLBCL) and Burkitt lymphoma, blastoid cases with a double-hit, and cases with a DLBCL, not otherwise specified, morphology with a double-hit. It refers only to de novo cases, not to lymphomas with a history of pre-existing or coexistent indolent lymphoma. Patients typically present with widespread disease, including involvement of lymph nodes, bone marrow, and central nervous system. Associated morphology True High grade B-cell lymphoma with MYC and BCL2 and/or BCL6 rearrangements (morphologic abnormality) Inferred relationship Some 1

This concept is not in any reference sets

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