Inbound Relationships |
Type |
Active |
Source |
Characteristic |
Refinability |
Group |
Ectopic hyperinsulinism |
Finding site |
True |
Endocrine pancreatic structure |
Inferred relationship |
Some |
1 |
Maternal diabetes mellitus with hypoglycemia affecting fetus OR newborn |
Finding site |
False |
Endocrine pancreatic structure |
Inferred relationship |
Some |
|
Hyperinsulinism |
Finding site |
True |
Endocrine pancreatic structure |
Inferred relationship |
Some |
1 |
Iatrogenic hyperinsulinism |
Finding site |
True |
Endocrine pancreatic structure |
Inferred relationship |
Some |
2 |
Post-surgical hypoinsulinemia |
Finding site |
True |
Endocrine pancreatic structure |
Inferred relationship |
Some |
2 |
Postpancreatectomy hypoinsulinemia |
Finding site |
True |
Endocrine pancreatic structure |
Inferred relationship |
Some |
1 |
Other hyperinsulinism |
Finding site |
False |
Endocrine pancreatic structure |
Inferred relationship |
Some |
|
Other hyperinsulinism NOS |
Finding site |
False |
Endocrine pancreatic structure |
Inferred relationship |
Some |
|
Post-surgical hyperglycemia NOS |
Finding site |
False |
Endocrine pancreatic structure |
Inferred relationship |
Some |
|
[X]Other specified disorders of pancreatic internal secretion |
Finding site |
False |
Endocrine pancreatic structure |
Inferred relationship |
Some |
|
Type I diabetes mellitus with complication |
Finding site |
False |
Endocrine pancreatic structure |
Inferred relationship |
Some |
|
Type I diabetes mellitus with ketoacidosis |
Finding site |
False |
Endocrine pancreatic structure |
Inferred relationship |
Some |
|
Type II diabetes mellitus with complication |
Finding site |
False |
Endocrine pancreatic structure |
Inferred relationship |
Some |
|
Diabetes mellitus with skin ulcer |
Finding site |
False |
Endocrine pancreatic structure |
Inferred relationship |
Some |
|
Diabetes mellitus with complication |
Finding site |
False |
Endocrine pancreatic structure |
Inferred relationship |
Some |
|
Procedure on endocrine pancreas (procedure) |
Procedure site |
True |
Endocrine pancreatic structure |
Inferred relationship |
Some |
1 |
Hyperplasia of islet alpha cells with gastrin excess |
Finding site |
False |
Endocrine pancreatic structure |
Inferred relationship |
Some |
3 |
Thyroid gland repair |
Procedure site |
False |
Endocrine pancreatic structure |
Inferred relationship |
Some |
1 |
Houssay's syndrome |
Finding site |
False |
Endocrine pancreatic structure |
Inferred relationship |
Some |
|
Hyperosmolar non-ketotic state due to type 2 diabetes mellitus |
Finding site |
False |
Endocrine pancreatic structure |
Inferred relationship |
Some |
|
Hyperplasia of pancreatic islet beta cell |
Finding site |
False |
Endocrine pancreatic structure |
Inferred relationship |
Some |
3 |
Diabetes mellitus with persistent microalbuminuria |
Finding site |
False |
Endocrine pancreatic structure |
Inferred relationship |
Some |
|
Diabetes mellitus with persistent proteinuria |
Finding site |
False |
Endocrine pancreatic structure |
Inferred relationship |
Some |
|
Type 1 diabetes mellitus with persistent proteinuria |
Finding site |
False |
Endocrine pancreatic structure |
Inferred relationship |
Some |
|
Type 1 diabetes mellitus with persistent microalbuminuria |
Finding site |
False |
Endocrine pancreatic structure |
Inferred relationship |
Some |
|
Type 2 diabetes mellitus with persistent proteinuria |
Finding site |
False |
Endocrine pancreatic structure |
Inferred relationship |
Some |
|
Type 2 diabetes mellitus with persistent microalbuminuria |
Finding site |
False |
Endocrine pancreatic structure |
Inferred relationship |
Some |
|
Type 1 diabetes mellitus with exudative maculopathy |
Finding site |
False |
Endocrine pancreatic structure |
Inferred relationship |
Some |
|
Type 2 diabetes mellitus with exudative maculopathy |
Finding site |
False |
Endocrine pancreatic structure |
Inferred relationship |
Some |
|
A rare endocrine disease characterised by hyperinsulinaemic hypoglycaemia associated with the presence of autoantibodies to endogenous insulin without previous exposure to exogenous insulin. Patients usually present in adulthood with postprandial, fasting or exercise-induced hypoglycaemia, often with pronounced neuroglycopenic symptoms. Laboratory investigations reveal markedly elevated serum insulin, as well as increased C-peptide and proinsulin. The condition may be associated with other autoimmune diseases, monoclonal gammopathy, and/or recent exposure to certain medications. |
Finding site |
True |
Endocrine pancreatic structure |
Inferred relationship |
Some |
1 |
Diabetes mellitus induced by non-steroid drugs |
Finding site |
False |
Endocrine pancreatic structure |
Inferred relationship |
Some |
|
Type II diabetes mellitus with ketoacidosis |
Finding site |
False |
Endocrine pancreatic structure |
Inferred relationship |
Some |
|
diabète sucré sans complication causé par un anti-inflammatoire non stéroïdien |
Finding site |
False |
Endocrine pancreatic structure |
Inferred relationship |
Some |
|
Excision of lesion of islet of Langerhans |
Procedure site - Direct (attribute) |
False |
Endocrine pancreatic structure |
Inferred relationship |
Some |
1 |
Idiopathic transient neonatal hyperinsulinaemia |
Finding site |
True |
Endocrine pancreatic structure |
Inferred relationship |
Some |
2 |
Hyperplasia of islet alpha cells with glucagon excess |
Finding site |
False |
Endocrine pancreatic structure |
Inferred relationship |
Some |
3 |
Insulin coma (disorder) |
Finding site |
False |
Endocrine pancreatic structure |
Inferred relationship |
Some |
|
Hypoglycaemic coma |
Finding site |
False |
Endocrine pancreatic structure |
Inferred relationship |
Some |
|
Hypoglycemic coma NOS |
Finding site |
False |
Endocrine pancreatic structure |
Inferred relationship |
Some |
|
Gestational diabetes mellitus, class B |
Finding site |
False |
Endocrine pancreatic structure |
Inferred relationship |
Some |
|
Gestational diabetes mellitus, class C |
Finding site |
False |
Endocrine pancreatic structure |
Inferred relationship |
Some |
|
Gestational diabetes mellitus, class D |
Finding site |
False |
Endocrine pancreatic structure |
Inferred relationship |
Some |
|
Gestational diabetes mellitus, class F |
Finding site |
False |
Endocrine pancreatic structure |
Inferred relationship |
Some |
|
Gestational diabetes mellitus, class R |
Finding site |
False |
Endocrine pancreatic structure |
Inferred relationship |
Some |
|
Gestational diabetes mellitus, class T |
Finding site |
False |
Endocrine pancreatic structure |
Inferred relationship |
Some |
|
Gestational diabetes mellitus, class H |
Finding site |
False |
Endocrine pancreatic structure |
Inferred relationship |
Some |
|
Endocrine gland repair |
Procedure site - Direct (attribute) |
False |
Endocrine pancreatic structure |
Inferred relationship |
Some |
1 |
Thyroid gland repair |
Procedure site - Direct (attribute) |
False |
Endocrine pancreatic structure |
Inferred relationship |
Some |
2 |
Transplantation of pancreatic islet cells (procedure) |
Procedure site - Direct (attribute) |
False |
Endocrine pancreatic structure |
Inferred relationship |
Some |
1 |
diabète sucré concomitant et dû à la mucoviscidose |
Finding site |
False |
Endocrine pancreatic structure |
Inferred relationship |
Some |
|
Latent autoimmune diabetes mellitus in adult (disorder) |
Finding site |
False |
Endocrine pancreatic structure |
Inferred relationship |
Some |
|
Diabetes mellitus due to cystic fibrosis (disorder) |
Finding site |
False |
Endocrine pancreatic structure |
Inferred relationship |
Some |
|
Zollinger-Ellison syndrome |
Finding site |
False |
Endocrine pancreatic structure |
Inferred relationship |
Some |
2 |
Transplantation of pancreatic islet cells (procedure) |
Procedure site - Indirect (attribute) |
False |
Endocrine pancreatic structure |
Inferred relationship |
Some |
1 |
Metastatic malignant neoplasm to islets of Langerhans |
Finding site |
True |
Endocrine pancreatic structure |
Inferred relationship |
Some |
1 |
Excision of lesion of islet of Langerhans |
Procedure site - Direct (attribute) |
True |
Endocrine pancreatic structure |
Inferred relationship |
Some |
2 |
Neoplasm of uncertain behavior of islets of Langerhans |
Finding site |
True |
Endocrine pancreatic structure |
Inferred relationship |
Some |
1 |
Primary malignant neoplasm of islets of Langerhans |
Finding site |
True |
Endocrine pancreatic structure |
Inferred relationship |
Some |
1 |
Multiple endocrine neoplasia, type 1 (disorder) |
Finding site |
False |
Endocrine pancreatic structure |
Inferred relationship |
Some |
1 |
Malignant neoplasm of Islets of Langerhans |
Finding site |
True |
Endocrine pancreatic structure |
Inferred relationship |
Some |
1 |
Gastrinoma |
Finding site |
False |
Endocrine pancreatic structure |
Inferred relationship |
Some |
1 |
Somatostatinoma |
Finding site |
False |
Endocrine pancreatic structure |
Inferred relationship |
Some |
2 |
insulinome |
Finding site |
False |
Endocrine pancreatic structure |
Inferred relationship |
Some |
2 |
Carcinoma in situ of islets of Langerhans |
Finding site |
True |
Endocrine pancreatic structure |
Inferred relationship |
Some |
1 |
Tumor of endocrine pancreas |
Finding site |
False |
Endocrine pancreatic structure |
Inferred relationship |
Some |
1 |
Endocrine pancreatic adenoma |
Finding site |
True |
Endocrine pancreatic structure |
Inferred relationship |
Some |
1 |
Transplantation of pancreatic islet cells (procedure) |
Procedure site - Indirect (attribute) |
False |
Endocrine pancreatic structure |
Inferred relationship |
Some |
1 |
tumeur carcinoide du pancréas |
Finding site |
False |
Endocrine pancreatic structure |
Inferred relationship |
Some |
1 |
Malignant neoplasm of endocrine pancreas (disorder) |
Finding site |
True |
Endocrine pancreatic structure |
Inferred relationship |
Some |
1 |
Mixed pancreatic endocrine tumor |
Finding site |
True |
Endocrine pancreatic structure |
Inferred relationship |
Some |
1 |
Human pancreatic polypeptide-secreting tumor |
Finding site |
False |
Endocrine pancreatic structure |
Inferred relationship |
Some |
1 |
Neoplasm of endocrine pancreas (disorder) |
Finding site |
True |
Endocrine pancreatic structure |
Inferred relationship |
Some |
1 |
néoplasme sécréteur de l'hormone de libération de l'hormone de croissance |
Finding site |
False |
Endocrine pancreatic structure |
Inferred relationship |
Some |
1 |
Benign islet cell tumor |
Finding site |
True |
Endocrine pancreatic structure |
Inferred relationship |
Some |
1 |
Vasoactive intestinal peptide-secreting tumour |
Finding site |
True |
Endocrine pancreatic structure |
Inferred relationship |
Some |
1 |
glucagonome |
Finding site |
False |
Endocrine pancreatic structure |
Inferred relationship |
Some |
1 |
Carcinoma of endocrine pancreas |
Finding site |
True |
Endocrine pancreatic structure |
Inferred relationship |
Some |
1 |
néoplasme neuroendocrine du pancréas sécrétant un peptide lié à la parathormone |
Finding site |
False |
Endocrine pancreatic structure |
Inferred relationship |
Some |
1 |
néoplasme sécrétant du peptide inhibiteur gastrique |
Finding site |
False |
Endocrine pancreatic structure |
Inferred relationship |
Some |
1 |
Multiple complications due to type 1 diabetes mellitus |
Finding site |
False |
Endocrine pancreatic structure |
Inferred relationship |
Some |
|
complications multiples du diabète sucré de type 2 |
Finding site |
False |
Endocrine pancreatic structure |
Inferred relationship |
Some |
|
Transplantation of pancreatic islet cells (procedure) |
Procedure site - Direct (attribute) |
False |
Endocrine pancreatic structure |
Inferred relationship |
Some |
1 |
Multiple complications due to diabetes mellitus |
Finding site |
False |
Endocrine pancreatic structure |
Inferred relationship |
Some |
|
Percutaneous transhepatic transplantation of pancreatic islet cells using fluoroscopic guidance (procedure) |
Procedure site - Direct (attribute) |
False |
Endocrine pancreatic structure |
Inferred relationship |
Some |
2 |
Transplantation of pancreatic islet cells (procedure) |
Procedure site - Direct (attribute) |
False |
Endocrine pancreatic structure |
Inferred relationship |
Some |
1 |
Posttransplant diabetes mellitus (disorder) |
Finding site |
False |
Endocrine pancreatic structure |
Inferred relationship |
Some |
|
Percutaneous transhepatic transplantation of pancreatic islet cells using fluoroscopic guidance (procedure) |
Procedure site - Direct (attribute) |
True |
Endocrine pancreatic structure |
Inferred relationship |
Some |
2 |
Renal cysts and diabetes syndrome |
Finding site |
False |
Endocrine pancreatic structure |
Inferred relationship |
Some |
|
Allotransplantation of islets of Langerhans (procedure) |
Procedure site - Direct (attribute) |
False |
Endocrine pancreatic structure |
Inferred relationship |
Some |
1 |
Hyperplasia of islet alpha cells with gastrin excess |
Finding site |
False |
Endocrine pancreatic structure |
Inferred relationship |
Some |
4 |
Hyperplasia of islet alpha cells with glucagon excess |
Finding site |
False |
Endocrine pancreatic structure |
Inferred relationship |
Some |
4 |
Hyperplasia of pancreatic islet beta cell |
Finding site |
False |
Endocrine pancreatic structure |
Inferred relationship |
Some |
4 |
Islet cell hyperplasia |
Finding site |
False |
Endocrine pancreatic structure |
Inferred relationship |
Some |
3 |
Islet cell hyperplasia |
Finding site |
False |
Endocrine pancreatic structure |
Inferred relationship |
Some |
1 |
Increased gastrin secretion |
Finding site |
False |
Endocrine pancreatic structure |
Inferred relationship |
Some |
|
Insulin reactive hypoglycemia due to type 2 diabetes mellitus (disorder) |
Finding site |
True |
Endocrine pancreatic structure |
Inferred relationship |
Some |
2 |
A rare form of congenital diazoxide-sensitive diffuse hyperinsulinism characterized by episodes of hypoglycemia induced by exercise due to an inappropriate lactate and pyruvate sensitivity in pancreatic beta-cells. Presentation is of recurring episodes of hypoglycemia associated with elevated insulin levels, within 30 minutes of a short period of anaerobic exercise. The degree of hypoglycemia associated with exercise is variable and is only partially responsive to diazoxide. |
Finding site |
False |
Endocrine pancreatic structure |
Inferred relationship |
Some |
|
A rare familial hyperinsulinism characterized by postprandial hyperinsulinemic hypoglycemia, negative 72-hour fasts, negative preoperative localization studies for insulinoma, and positive selective arterial calcium infusion tests. Histopathological analysis reveals diffuse islet hyperplasia with increased number and size of islet cells. |
Finding site |
True |
Endocrine pancreatic structure |
Inferred relationship |
Some |
2 |
A form of diazoxide-sensitive diffuse hyperinsulinism (DHI) characterized by hypoglycemic episodes that are usually mild, escaping detection during infancy, and usually a good clinical response to diazoxide, (but some are diazoxide resistant). Autosomal dominant hyperinsulinism due to Kir6.2 deficiency usually has a milder phenotype when compared to that resulting from recessive K+ (K-ATP) channel mutations (recessive forms of diazoxide-resistant hyperinsulinism). |
Finding site |
False |
Endocrine pancreatic structure |
Inferred relationship |
Some |
|
A form of congenital diazoxide-sensitive diffuse hyperinsulinism due to ABCC8 variants and characterized by hypoglycemic episodes that are usually mild, escaping detection during infancy, and usually have a good clinical response to diazoxide. The autosomal dominant hyperinsulinism usually has a milder phenotype when compared to that resulting from recessive potassium (K-ATP) channel mutations. |
Finding site |
False |
Endocrine pancreatic structure |
Inferred relationship |
Some |
|
A form of diazoxide-sensitive diffuse congenital hyperinsulinism due to HNF4A deficiency and, characterised by macrosomia, transient or persistent hyperinsulinaemic hypoglycaemia (HH), responsiveness to diazoxide and a propensity to develop maturity-onset diabetes of the young subtype 1 (MODY). |
Finding site |
False |
Endocrine pancreatic structure |
Inferred relationship |
Some |
|