819963008: Brolucizumab (substance)

SNOMED CT Concept\Substance\...

\Substance categorized by disposition\Substance with receptor antagonist mechanism of action (substance)\Substance with vascular endothelial growth factor receptor antagonist mechanism of action (substance)\Brolucizumab (substance)

\A grouper concept for substances that are used in medicinal products for medical treatment, and also psychoactive substances that have few or no legitimate medical uses or that are not legally available to the person using them.\Monoclonal antibody\Brolucizumab (substance)

\Substance categorised by structure\Chemical\Chemical categorized by structure (substance)\...

\Nitrogen and/or nitrogen compound (substance)\Nitrogen compound\Organic nitrogen compound\Amide and/or amide derivative (substance)\Substituted amide (substance)\Polypeptide\Protein\Antibody\Monoclonal antibody\Brolucizumab (substance)

\Organic compound\Organic nitrogen compound\Amide and/or amide derivative (substance)\Substituted amide (substance)\Polypeptide\Protein\Antibody\Monoclonal antibody\Brolucizumab (substance)

\Biological substance\Protein and/or protein derivative\Protein\Antibody\Monoclonal antibody\Brolucizumab (substance)
\Biological substance\Immunologic substance\Antibody\Monoclonal antibody\Brolucizumab (substance)
\Biological substance\Polypeptide\Protein\Antibody\Monoclonal antibody\Brolucizumab (substance)

Status: current, Not sufficiently defined by necessary conditions definition status (core metadata concept). Date: 31-Jan 2020. Module: SNOMED CT core

Descriptions:

Id Description Lang Type Status Case? Module

3858363017 Brolucizumab (substance) en Fully specified name Active Entire term case insensitive (core metadata concept) SNOMED CT core

3858364011 Brolucizumab en Synonym (core metadata concept) Active Entire term case insensitive (core metadata concept) SNOMED CT core

369161000195110 brolucizumab it Synonym (core metadata concept) Active Entire term case insensitive (core metadata concept) SNOMED CT Switzerland NRC maintained Module

1132981000241114 brolucizumab fr Synonym (core metadata concept) Active Entire term case insensitive (core metadata concept) SNOMED CT Switzerland NRC maintained Module

Expanded Value Set

Outbound Relationships	Type	Target	Active	Characteristic	Refinability	Group	Values
Brolucizumab (substance)	Is a	Monoclonal antibody	true	Inferred relationship	Some
Brolucizumab (substance)	This attribute specifies the behavior that a substance will exhibit or participate in, given the appropriate context.	Vascular endothelial growth factor receptor antagonist (disposition)	true	Inferred relationship	Some
Brolucizumab (substance)	Is a	Substance with vascular endothelial growth factor receptor antagonist mechanism of action (substance)	true	Inferred relationship	Some

Inbound Relationships	Type	Active	Source	Characteristic	Refinability	Group
Brolucizumab only product	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Brolucizumab (substance)	Inferred relationship	Some	1
Brolucizumab-containing product	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Brolucizumab (substance)	Inferred relationship	Some	1
Brolucizumab-containing product in parenteral dose form	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Brolucizumab (substance)	Inferred relationship	Some	1
Product containing only brolucizumab in parenteral dose form (medicinal product form)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Brolucizumab (substance)	Inferred relationship	Some	1
Product containing precisely brolucizumab 120 milligram/1 milliliter conventional release solution for injection (clinical drug)	The most specific description of a substance present in the manufactured dose form, before any dilution or transformation. It includes modifiers, such as salts, esters, polymers (e.g. pegylation), and/or solvates (including waters of hydration).	True	Brolucizumab (substance)	Inferred relationship	Some	1
Product containing precisely brolucizumab 120 milligram/1 milliliter conventional release solution for injection (clinical drug)	This attribute represents an ingredient that is the part of the active ingredient that the strength of a given product is based upon.	True	Brolucizumab (substance)	Inferred relationship	Some	1

Reference Sets