Inbound Relationships |
Type |
Active |
Source |
Characteristic |
Refinability |
Group |
Testicular hyperfunction |
Interprets |
False |
Increased hormone production |
Inferred relationship |
Some |
|
Multiple endocrine neoplasia, type 1 (disorder) |
Interprets |
False |
Increased hormone production |
Inferred relationship |
Some |
|
Hyperestrogenism |
Interprets |
False |
Increased hormone production |
Inferred relationship |
Some |
|
Polyglandular activity in multiple endocrine adenomatosis |
Interprets |
False |
Increased hormone production |
Inferred relationship |
Some |
|
Multiple endocrine neoplasia, type 2b |
Interprets |
False |
Increased hormone production |
Inferred relationship |
Some |
|
Multiple endocrine neoplasia, type 2 |
Interprets |
False |
Increased hormone production |
Inferred relationship |
Some |
|
Testicular hyperfunction |
Has definitional manifestation |
False |
Increased hormone production |
Inferred relationship |
Some |
|
Hyperestrogenism |
Has definitional manifestation |
False |
Increased hormone production |
Inferred relationship |
Some |
|
Pituitary dependent hypercortisolism |
Has definitional manifestation |
False |
Increased hormone production |
Inferred relationship |
Some |
|
Hyperpituitarism |
Has definitional manifestation |
False |
Increased hormone production |
Inferred relationship |
Some |
|
Thyrotoxicosis due to TSHoma |
Has definitional manifestation |
False |
Increased hormone production |
Inferred relationship |
Some |
|
Hyperprolactinemia |
Has definitional manifestation |
False |
Increased hormone production |
Inferred relationship |
Some |
|
Idiopathic hyperprolactinaemia |
Has definitional manifestation |
False |
Increased hormone production |
Inferred relationship |
Some |
|
Pituitary stalk compression hyperprolactinemia |
Has definitional manifestation |
False |
Increased hormone production |
Inferred relationship |
Some |
|
Drug-induced hyperprolactinaemia |
Has definitional manifestation |
False |
Increased hormone production |
Inferred relationship |
Some |
|
Physiological hyperprolactinemia |
Has definitional manifestation |
False |
Increased hormone production |
Inferred relationship |
Some |
|
Lactation hyperprolactinaemia |
Has definitional manifestation |
False |
Increased hormone production |
Inferred relationship |
Some |
|
Pregnancy hyperprolactinemia |
Has definitional manifestation |
False |
Increased hormone production |
Inferred relationship |
Some |
|
ACTH hypersecretion |
Has definitional manifestation |
False |
Increased hormone production |
Inferred relationship |
Some |
|
ACTH hypersecretion not causing Cushing's syndrome |
Has definitional manifestation |
False |
Increased hormone production |
Inferred relationship |
Some |
|
Gonadotrophin hypersecretion |
Has definitional manifestation |
False |
Increased hormone production |
Inferred relationship |
Some |
|
Luteinizing hormone hypersecretion (disorder) |
Has definitional manifestation |
False |
Increased hormone production |
Inferred relationship |
Some |
|
FSH hypersecretion |
Has definitional manifestation |
False |
Increased hormone production |
Inferred relationship |
Some |
|
Adrenal hyperfunction |
Has definitional manifestation |
False |
Increased hormone production |
Inferred relationship |
Some |
|
Catecholamine hypersecretion |
Has definitional manifestation |
False |
Increased hormone production |
Inferred relationship |
Some |
|
Medulloadrenal hyperfunction (disorder) |
Has definitional manifestation |
False |
Increased hormone production |
Inferred relationship |
Some |
|
Gigantism and acromegaly |
Has definitional manifestation |
False |
Increased hormone production |
Inferred relationship |
Some |
|
Gigantism due to somatostatin deficiency |
Has definitional manifestation |
False |
Increased hormone production |
Inferred relationship |
Some |
|
Prepuberal hyperpituitarism |
Has definitional manifestation |
False |
Increased hormone production |
Inferred relationship |
Some |
|
Thyrotoxicosis due to pituitary thyroid hormone resistance |
Has definitional manifestation |
False |
Increased hormone production |
Inferred relationship |
Some |
|
Thyrotoxicosis due to overproduction of thyroid stimulating hormone |
Has definitional manifestation |
False |
Increased hormone production |
Inferred relationship |
Some |
|
Thyrotoxicosis due to inappropriate TSH secretion |
Has definitional manifestation |
False |
Increased hormone production |
Inferred relationship |
Some |
|
Eunuchoid gigantism |
Has definitional manifestation |
False |
Increased hormone production |
Inferred relationship |
Some |
|
Secondary hyperprolactinemia |
Has definitional manifestation |
False |
Increased hormone production |
Inferred relationship |
Some |
|
Overproduction of growth hormone |
Has definitional manifestation |
False |
Increased hormone production |
Inferred relationship |
Some |
|
Myopathy in Cushing's disease |
Has definitional manifestation |
False |
Increased hormone production |
Inferred relationship |
Some |
|
Non-pregnancy related A-G syndrome |
Has definitional manifestation |
False |
Increased hormone production |
Inferred relationship |
Some |
|
Thyrotropin overproduction |
Has definitional manifestation |
False |
Increased hormone production |
Inferred relationship |
Some |
|
Acromegaly |
Has definitional manifestation |
False |
Increased hormone production |
Inferred relationship |
Some |
|
Hagner's disease |
Has definitional manifestation |
False |
Increased hormone production |
Inferred relationship |
Some |
|
Sotos' syndrome |
Has definitional manifestation |
False |
Increased hormone production |
Inferred relationship |
Some |
|
Secondary hyperprolactinemia due to prolactin-secreting tumor (disorder) |
Has definitional manifestation |
False |
Increased hormone production |
Inferred relationship |
Some |
|
Gigantism |
Has definitional manifestation |
False |
Increased hormone production |
Inferred relationship |
Some |
|
Beckwith-Wiedemann syndrome |
Has definitional manifestation |
False |
Increased hormone production |
Inferred relationship |
Some |
|
Postpartum amenorrhoea-galactorrhea syndrome |
Has definitional manifestation |
False |
Increased hormone production |
Inferred relationship |
Some |
|
Hypersomatotropic gigantism |
Has definitional manifestation |
False |
Increased hormone production |
Inferred relationship |
Some |
|
Transient hyperprolactinemia |
Has definitional manifestation |
False |
Increased hormone production |
Inferred relationship |
Some |
|
Renon-Delille syndrome |
Has definitional manifestation |
False |
Increased hormone production |
Inferred relationship |
Some |
|
Adrenocortical hyperfunction |
Has definitional manifestation |
False |
Increased hormone production |
Inferred relationship |
Some |
|
Disorders of growth hormone excess NOS |
Has definitional manifestation |
False |
Increased hormone production |
Inferred relationship |
Some |
|
[X]Other adrenocortical overactivity |
Has definitional manifestation |
False |
Increased hormone production |
Inferred relationship |
Some |
|
Other anterior pituitary hyperfunction |
Has definitional manifestation |
False |
Increased hormone production |
Inferred relationship |
Some |
|
Other corticoadrenal overactivity |
Has definitional manifestation |
False |
Increased hormone production |
Inferred relationship |
Some |
|
Simpson-Golabi-Behmel syndrome (disorder) |
Has definitional manifestation |
False |
Increased hormone production |
Inferred relationship |
Some |
|
X-linked intellectual disability-acromegaly-hyperactivity syndrome is characterized by severe intellectual deficit, acromegaly and hyperactivity. The syndrome has been described in two half-brothers. Dysarthria, aggressive behavior, a characteristic facies (an acromegalic and triangular face with a long nose) and macroorchidism were also present. The mother displayed moderate intellectual deficit and milder facial anomalies. Central nervous system anomalies were identified in the two boys: subarachnoid cysts and hyperdensity in the pontine region. |
Has definitional manifestation |
False |
Increased hormone production |
Inferred relationship |
Some |
|
Macroprolactinemia (disorder) |
Has definitional manifestation |
False |
Increased hormone production |
Inferred relationship |
Some |
|
Familial male limited precocious puberty (FMPP) is a gonadotropin-independent familial form of male-limited precocious puberty, generally presenting between 2-5 years of age as accelerated growth, early development of secondary sexual characteristics and reduced adult height. |
Is a |
True |
Increased hormone production |
Inferred relationship |
Some |
|
Transient infantile hyperthyrotropinemia (disorder) |
Has definitional manifestation |
False |
Increased hormone production |
Inferred relationship |
Some |
|
Adrenocortical hyperfunction |
Is a |
False |
Increased hormone production |
Inferred relationship |
Some |
|
Gigantism |
Is a |
False |
Increased hormone production |
Inferred relationship |
Some |
|
X-linked intellectual disability-acromegaly-hyperactivity syndrome is characterized by severe intellectual deficit, acromegaly and hyperactivity. The syndrome has been described in two half-brothers. Dysarthria, aggressive behavior, a characteristic facies (an acromegalic and triangular face with a long nose) and macroorchidism were also present. The mother displayed moderate intellectual deficit and milder facial anomalies. Central nervous system anomalies were identified in the two boys: subarachnoid cysts and hyperdensity in the pontine region. |
Is a |
False |
Increased hormone production |
Inferred relationship |
Some |
|
Pseudoleprechaunism syndrome, Patterson type is a rare, genetic, adrenal disorder characterized by congenital bronzed hyperpigmentation, cutis laxa of the hands and feet, body disproportion (comprising large hands, feet, nose and ears), hirsutism and severe intellectual disability. Patients additionally present hyperadrenocorticism, cushingoid features, premature adrenarche and diabetes mellitus, as well as skeletal deformities (not present at birth and which progress with age). There have been no further descriptions in the literature since 1981. |
Is a |
False |
Increased hormone production |
Inferred relationship |
Some |
|
Hyperestrogenism |
Is a |
True |
Increased hormone production |
Inferred relationship |
Some |
|
Hyperpituitarism |
Is a |
True |
Increased hormone production |
Inferred relationship |
Some |
|
Adrenal hyperfunction |
Is a |
True |
Increased hormone production |
Inferred relationship |
Some |
|