Inbound Relationships |
Type |
Active |
Source |
Characteristic |
Refinability |
Group |
Angioedema |
Associated morphology |
True |
Angioedema |
Inferred relationship |
Some |
1 |
Food-induced angioedema-urticaria (disorder) |
Associated morphology |
True |
Angioedema |
Inferred relationship |
Some |
2 |
Drug-aggravated angioedema-urticaria (disorder) |
Associated morphology |
True |
Angioedema |
Inferred relationship |
Some |
2 |
Episodic angioedema with eosinophilia (disorder) |
Associated morphology |
True |
Angioedema |
Inferred relationship |
Some |
1 |
Angioedema due to disorder of kinin metabolism |
Associated morphology |
True |
Angioedema |
Inferred relationship |
Some |
1 |
Vibratory angioedema (disorder) |
Associated morphology |
True |
Angioedema |
Inferred relationship |
Some |
1 |
Venom-induced angioedema-urticaria (disorder) |
Associated morphology |
True |
Angioedema |
Inferred relationship |
Some |
2 |
Physical angioedema (disorder) |
Associated morphology |
True |
Angioedema |
Inferred relationship |
Some |
1 |
Cholinergic angioedema (disorder) |
Associated morphology |
True |
Angioedema |
Inferred relationship |
Some |
1 |
Angioedema of tongue (disorder) |
Associated morphology |
True |
Angioedema |
Inferred relationship |
Some |
1 |
Angioedema of eyelid (disorder) |
Associated morphology |
True |
Angioedema |
Inferred relationship |
Some |
1 |
Angioedema of lip (disorder) |
Associated morphology |
True |
Angioedema |
Inferred relationship |
Some |
1 |
Penicillin-induced angioedema-urticaria (disorder) |
Associated morphology |
True |
Angioedema |
Inferred relationship |
Some |
2 |
Idiopathic angioedema (disorder) |
Associated morphology |
True |
Angioedema |
Inferred relationship |
Some |
1 |
ACE inhibitor-aggravated angioedema |
Associated morphology |
True |
Angioedema |
Inferred relationship |
Some |
1 |
Aspirin-induced angioedema-urticaria (disorder) |
Associated morphology |
True |
Angioedema |
Inferred relationship |
Some |
2 |
Autoimmune angioedema (disorder) |
Associated morphology |
True |
Angioedema |
Inferred relationship |
Some |
1 |
Chemical-aggravated angioedema-urticaria (disorder) |
Associated morphology |
True |
Angioedema |
Inferred relationship |
Some |
2 |
Respiratory angioedema |
Associated morphology |
True |
Angioedema |
Inferred relationship |
Some |
1 |
A rare non-histaminic angioedema characterised by potentially life-threatening episodes of oedema of subcutaneous and/or mucosal tissues without urticaria, caused by excessive consumption of C1 esterase inhibitor (C1-INH) in the context of lymphoproliferative or autoimmune diseases. Patients typically present in the fourth decade of life or later and without a family history of angioedema. Clinical manifestation includes nonpitting oedema of the skin predominantly involving the face, but also the limbs or genitals, as well as abdominal pain due to involvement of the gastrointestinal mucosa and severe oedema of the upper airway and oral mucosa. Laboratory examination shows low C1-INH activity and low C3, C4, and C1q levels. Autoantibodies to C1-INH are frequently detectable. |
Associated morphology |
True |
Angioedema |
Inferred relationship |
Some |
1 |
Acquired angio-oedema due to the presence of neutralising antibodies against C1 inhibitor. |
Associated morphology |
True |
Angioedema |
Inferred relationship |
Some |
1 |
Azo-dye-induced angioedema-urticaria (disorder) |
Associated morphology |
True |
Angioedema |
Inferred relationship |
Some |
2 |
Sodium benzoate-induced angioedema-urticaria (disorder) |
Associated morphology |
True |
Angioedema |
Inferred relationship |
Some |
2 |
Latex-induced angioedema-urticaria |
Associated morphology |
False |
Angioedema |
Inferred relationship |
Some |
2 |
Allergic angioedema (disorder) |
Associated morphology |
True |
Angioedema |
Inferred relationship |
Some |
1 |
Allergic angioedema due to bite and/or sting (disorder) |
Associated morphology |
True |
Angioedema |
Inferred relationship |
Some |
1 |
Allergic angioedema due to ingested food (disorder) |
Associated morphology |
True |
Angioedema |
Inferred relationship |
Some |
1 |
Angioedema caused by angiotensin-converting-enzyme inhibitor (disorder) |
Associated morphology |
True |
Angioedema |
Inferred relationship |
Some |
1 |
Intestinal angioedema caused by angiotensin-converting enzyme inhibitor (disorder) |
Associated morphology |
True |
Angioedema |
Inferred relationship |
Some |
1 |
NSAID-induced angioedema-urticaria |
Associated morphology |
True |
Angioedema |
Inferred relationship |
Some |
2 |
ACE inhibitor-aggravated angioedema |
Associated morphology |
True |
Angioedema |
Inferred relationship |
Some |
2 |
Hereditary angioedema (HAE) is a genetic disease characterized by the occurrence of transitory and recurrent subcutaneous and/or submucosal edemas resulting in swelling and/or abdominal pain. |
Associated morphology |
True |
Angioedema |
Inferred relationship |
Some |
1 |
Hereditary C1 esterase inhibitor deficiency - deficient factor |
Associated morphology |
True |
Angioedema |
Inferred relationship |
Some |
1 |
Hereditary C1 esterase inhibitor deficiency - dysfunctional factor |
Associated morphology |
True |
Angioedema |
Inferred relationship |
Some |
1 |
Hereditary angioedema without abnormal C1 inhibitor levels or function. One type has been found mostly in females in which symptoms may be triggered by pregnancy or estrogen-containing oral contraceptives. Mechanisms include mutations of the genes encoding coagulation factor XII, angiopoietin-1, plasminogen and as yet undefined factors. |
Associated morphology |
True |
Angioedema |
Inferred relationship |
Some |
1 |
Angioedema caused by angiotensin-converting-enzyme inhibitor (disorder) |
Associated morphology |
True |
Angioedema |
Inferred relationship |
Some |
2 |
Intestinal angioedema caused by angiotensin-converting enzyme inhibitor (disorder) |
Associated morphology |
True |
Angioedema |
Inferred relationship |
Some |
2 |
Acquired angioedema due to activation of the classical complement pathway related to an underlying lymphoreticular disorder particularly lymphoma or monoclonal gammopathy of unknown significance (MGUS) |
Associated morphology |
True |
Angioedema |
Inferred relationship |
Some |
1 |
Drug-induced angioedema-urticaria (disorder) |
Associated morphology |
True |
Angioedema |
Inferred relationship |
Some |
2 |
Hevea brasiliensis latex protein-induced angioedema-urticaria |
Associated morphology |
True |
Angioedema |
Inferred relationship |
Some |
2 |
Angioedema of gingiva due to deficiency of C1 esterase inhibitor |
Associated morphology |
True |
Angioedema |
Inferred relationship |
Some |
1 |
A rare hereditary angioedema characterized by potentially life-threatening episodes of subcutaneous and/or submucosal edema without urticaria, associated with C1 esterase inhibitor (C1-INH) deficiency. Hereditary angioedema (HAE) type 1 is caused by quantitative, HAE type 2 by qualitative defects of C1-INH. The two subtypes are clinically indistinguishable. Patients may present at any age (but most commonly in childhood) with recurrent attacks of nonpitting edema of the skin, severe abdominal symptoms such as pain and swelling, and/or respiratory distress due to upper respiratory airways involvement. Genital, bladder, muscle, or joint swelling may occur in some cases. |
Associated morphology |
True |
Angioedema |
Inferred relationship |
Some |
1 |
Acquired angioedema type II (disorder) |
Associated morphology |
True |
Angioedema |
Inferred relationship |
Some |
1 |
Acquired angioedema type I (disorder) |
Associated morphology |
True |
Angioedema |
Inferred relationship |
Some |
1 |