870689004: Selumetinib (substance)

SNOMED CT Concept\Substance\...

\Substance categorized by disposition\Substance with effector mechanism of action (substance)\Enzyme inhibitor\Transferase inhibitor\Phosphotransferase inhibitor\Protein kinase inhibitor\Substance with mitogen-activated protein kinase kinase inhibitor mechanism of action (substance)\Selumetinib (substance)

\A grouper concept for substances that are used in medicinal products for medical treatment, and also psychoactive substances that have few or no legitimate medical uses or that are not legally available to the person using them.\Antineoplastic agent (substance)\Selumetinib (substance)

\Substance categorised by structure\Chemical\Chemical categorized by structure (substance)\Organic compound\Organic cyclic compound\Heterocyclic compound\Benzimidazole (substance)\Selumetinib (substance)

Status: current, Not sufficiently defined by necessary conditions definition status (core metadata concept). Date: 31-Jul 2020. Module: SNOMED CT core

Descriptions:

Id Description Lang Type Status Case? Module

3970852010 Selumetinib (substance) en Fully specified name Active Entire term case insensitive (core metadata concept) SNOMED CT core

3970853017 Selumetinib en Synonym (core metadata concept) Active Entire term case insensitive (core metadata concept) SNOMED CT core

Expanded Value Set

Outbound Relationships	Type	Target	Active	Characteristic	Refinability	Group	Values
Selumetinib (substance)	Is a	Enzyme inhibitor	false	Inferred relationship	Some
Selumetinib (substance)	Is a	Benzimidazole (substance)	true	Inferred relationship	Some
Selumetinib (substance)	Is a	Substance with mitogen-activated protein kinase kinase inhibitor mechanism of action (substance)	true	Inferred relationship	Some
Selumetinib (substance)	Is a	Antineoplastic agent (substance)	true	Inferred relationship	Some
Selumetinib (substance)	This attribute specifies the behavior that a substance will exhibit or participate in, given the appropriate context.	Mitogen-activated protein kinase kinase inhibitor (disposition)	true	Inferred relationship	Some

Inbound Relationships	Type	Active	Source	Characteristic	Refinability	Group
Product containing selumetinib (medicinal product)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Selumetinib (substance)	Inferred relationship	Some	1
Selumetinib only product	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Selumetinib (substance)	Inferred relationship	Some	1
Selumetinib-containing product in oral dose form	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Selumetinib (substance)	Inferred relationship	Some	1
Selumetinib only product in oral dose form	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Selumetinib (substance)	Inferred relationship	Some	1
Product containing precisely selumetinib 25 milligram/1 each conventional release oral capsule (clinical drug)	This attribute represents an ingredient that is the part of the active ingredient that the strength of a given product is based upon.	False	Selumetinib (substance)	Inferred relationship	Some	1
Product containing precisely selumetinib 25 milligram/1 each conventional release oral capsule (clinical drug)	The most specific description of a substance present in the manufactured dose form, before any dilution or transformation. It includes modifiers, such as salts, esters, polymers (e.g. pegylation), and/or solvates (including waters of hydration).	False	Selumetinib (substance)	Inferred relationship	Some	1
Product containing precisely selumetinib 10 milligram/1 each conventional release oral capsule (clinical drug)	This attribute represents an ingredient that is the part of the active ingredient that the strength of a given product is based upon.	False	Selumetinib (substance)	Inferred relationship	Some	1
Product containing precisely selumetinib 10 milligram/1 each conventional release oral capsule (clinical drug)	The most specific description of a substance present in the manufactured dose form, before any dilution or transformation. It includes modifiers, such as salts, esters, polymers (e.g. pegylation), and/or solvates (including waters of hydration).	False	Selumetinib (substance)	Inferred relationship	Some	1
Selumetinib sulfate (substance)	This attribute indicates that the concept is a structural modification of another concept, and that the substance's intrinsic physicochemical properties remain unchanged.	True	Selumetinib (substance)	Inferred relationship	Some
Selumetinib (as selumetinib hydrogen sulfate) 10 mg oral capsule	This attribute represents an ingredient that is the part of the active ingredient that the strength of a given product is based upon.	True	Selumetinib (substance)	Inferred relationship	Some	1
Product containing precisely selumetinib (as selumetinib hydrogen sulfate) 25 milligram/1 each conventional release oral capsule (clinical drug)	This attribute represents an ingredient that is the part of the active ingredient that the strength of a given product is based upon.	True	Selumetinib (substance)	Inferred relationship	Some	1

This concept is not in any reference sets