Inbound Relationships |
Type |
Active |
Source |
Characteristic |
Refinability |
Group |
Serum dihydropyrimide dehydrogenase level (procedure) |
Component |
False |
Enzyme |
Inferred relationship |
Some |
|
Serum tissue transglutaminase level (procedure) |
Component |
True |
Enzyme |
Inferred relationship |
Some |
1 |
Cardiac markers |
Component |
False |
Enzyme |
Inferred relationship |
Some |
1 |
Blood thiopurine methyltransferase level (procedure) |
Component |
False |
Enzyme |
Inferred relationship |
Some |
|
Streptokinase (substance) |
Is a |
False |
Enzyme |
Inferred relationship |
Some |
|
Product containing bromelains (medicinal product) |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Enzyme |
Inferred relationship |
Some |
|
Thrombolytic agent |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Enzyme |
Inferred relationship |
Some |
|
Proteolytic enzyme preparation |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Enzyme |
Inferred relationship |
Some |
|
Product containing laronidase (medicinal product) |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Enzyme |
Inferred relationship |
Some |
|
Substance with red blood cell enzyme mechanism of action |
Is a |
False |
Enzyme |
Inferred relationship |
Some |
|
Substance with white blood cell enzyme mechanism of action |
Is a |
False |
Enzyme |
Inferred relationship |
Some |
|
médicament thrombolytique |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Enzyme |
Inferred relationship |
Some |
|
Enzyme deficiency product |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Enzyme |
Inferred relationship |
Some |
|
Product containing drotrecogin alfa (activated) |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Enzyme |
Inferred relationship |
Some |
|
Drotrecogin alfa (activated) 5mg powder for infusion solution vial |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Enzyme |
Inferred relationship |
Some |
|
Product containing precisely drotrecogin alfa 20 milligram/1 vial powder for conventional release solution for injection (clinical drug) |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Enzyme |
Inferred relationship |
Some |
|
Product containing miglustat (medicinal product) |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Enzyme |
Inferred relationship |
Some |
|
Product containing carglumic acid (medicinal product) |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Enzyme |
Inferred relationship |
Some |
|
Carglutamic acid 200mg dispersible tablet |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Enzyme |
Inferred relationship |
Some |
|
Carglumic acid 200mg dispersible tablet |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Enzyme |
Inferred relationship |
Some |
|
Miglustat 100 mg oral capsule |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Enzyme |
Inferred relationship |
Some |
|
Urokinase (substance) |
Is a |
False |
Enzyme |
Inferred relationship |
Some |
|
Product containing recombinant levo iduronidase (medicinal product) |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Enzyme |
Inferred relationship |
Some |
|
Laronidase 2.9mg/5mL injection solution 5mL vial |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Enzyme |
Inferred relationship |
Some |
|
Product containing plasminogen activator (product) |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Enzyme |
Inferred relationship |
Some |
|
Enzyme immunoassay method (procedure) |
Component |
True |
Enzyme |
Inferred relationship |
Some |
1 |
Carglutamic acid 200mg dispersible tablet |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Enzyme |
Inferred relationship |
Some |
|
Microbial antigen assay by enzyme immunoassay (EIA) method |
Component |
False |
Enzyme |
Inferred relationship |
Some |
3 |
Product containing collagenase (medicinal product) |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Enzyme |
Inferred relationship |
Some |
|
Glycoasparaginase level |
Component |
False |
Enzyme |
Inferred relationship |
Some |
|
Product containing streptokinase (medicinal product) |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Enzyme |
Inferred relationship |
Some |
|
streptokinase 1 500 000 U.I., fiole de poudre pour perfusion |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Enzyme |
Inferred relationship |
Some |
|
streptokinase 250 000 U.I., fiole de poudre pour perfusion |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Enzyme |
Inferred relationship |
Some |
|
streptokinase 750 000 U.I., fiole de poudre pour perfusion |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Enzyme |
Inferred relationship |
Some |
|
Adverse reaction to enzymes |
Causative agent (attribute) |
True |
Enzyme |
Inferred relationship |
Some |
1 |
Adverse reaction to enzymes NEC |
Causative agent (attribute) |
False |
Enzyme |
Inferred relationship |
Some |
|
Adverse reaction to enzymes NOS |
Causative agent (attribute) |
False |
Enzyme |
Inferred relationship |
Some |
|
Streptokinase 600000iu/vial powder |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Enzyme |
Inferred relationship |
Some |
|
Streptokinase 750000unt intravenous infusion vial |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Enzyme |
Inferred relationship |
Some |
|
Streptokinase 1500000unt intravenous infusion vial |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Enzyme |
Inferred relationship |
Some |
|
Streptokinase 250000unt intravenous infusion vial |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Enzyme |
Inferred relationship |
Some |
|
Proenzyme |
Is a |
True |
Enzyme |
Inferred relationship |
Some |
|
A substance containing enzymes, mainly lipase, with amylase and protease, obtained from the pancreas of the hog. It is a cream-coloured, amorphous powder having a faint characteristic, but not offensive odour. Its greatest activities are in neutral or faintly alkaline media; more than traces of mineral acids or large amounts of alkali hydroxides make it inert. An excess of alkali carbonate also inhibits its action. Pancrelipase contains, in each mg, not less than 24 USP units of lipase activity, not less than 100 USP units of amylase activity, and not less than 100 USP units of protease activity. |
Is a |
False |
Enzyme |
Inferred relationship |
Some |
|
Holo-[acyl-carrier-protein] synthase |
Is a |
False |
Enzyme |
Inferred relationship |
Some |
|
Chemonucleolysis |
Direct substance |
False |
Enzyme |
Inferred relationship |
Some |
1 |
Injection of spinal intervertebral space with chymopapain (procedure) |
Direct substance |
False |
Enzyme |
Inferred relationship |
Some |
1 |
Injection of spinal intervertebral space with chymotrypsin |
Direct substance |
False |
Enzyme |
Inferred relationship |
Some |
1 |
Lipoprotein associated phospholipase A₂ measurement (procedure) |
Component |
True |
Enzyme |
Inferred relationship |
Some |
1 |
Blood acid esterase measurement (procedure) |
Component |
False |
Enzyme |
Inferred relationship |
Some |
3 |
Oleate measurement (procedure) |
Component |
True |
Enzyme |
Inferred relationship |
Some |
1 |
Pancreatic enzyme (substance) |
Is a |
True |
Enzyme |
Inferred relationship |
Some |
|
Sebelipase alfa (substance) |
Is a |
False |
Enzyme |
Inferred relationship |
Some |
|
GDP-mannose 3,5-epimerase |
Is a |
False |
Enzyme |
Inferred relationship |
Some |
|
Chondroitin-glucuronate 5-epimerase |
Is a |
False |
Enzyme |
Inferred relationship |
Some |
|
Muconate cycloisomerase |
Is a |
False |
Enzyme |
Inferred relationship |
Some |
|
Aspartate racemase |
Is a |
False |
Enzyme |
Inferred relationship |
Some |
|
1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino]imidazole-4-carboxamide isomerase |
Is a |
False |
Enzyme |
Inferred relationship |
Some |
|
Nocardicin-A epimerase |
Is a |
False |
Enzyme |
Inferred relationship |
Some |
|
Alpha-methylacyl-CoA racemase |
Is a |
False |
Enzyme |
Inferred relationship |
Some |
|
Mannose-6-phosphate isomerase |
Is a |
False |
Enzyme |
Inferred relationship |
Some |
|
Triose-phosphate isomerase |
Is a |
False |
Enzyme |
Inferred relationship |
Some |
|
2-chloro-4-carboxymethylenebut-2-en-1,4-olide isomerase |
Is a |
False |
Enzyme |
Inferred relationship |
Some |
|
Muconolactone delta-isomerase |
Is a |
False |
Enzyme |
Inferred relationship |
Some |
|
Prostaglandin-A>1< delta-isomerase |
Is a |
False |
Enzyme |
Inferred relationship |
Some |
|
4-hydroxyphenylacetaldehyde-oxime isomerase |
Is a |
False |
Enzyme |
Inferred relationship |
Some |
|
Retinol isomerase |
Is a |
False |
Enzyme |
Inferred relationship |
Some |
|
Ribose isomerase |
Is a |
False |
Enzyme |
Inferred relationship |
Some |
|
Carboxyvinyl-carboxyphosphonate phosphorylmutase |
Is a |
False |
Enzyme |
Inferred relationship |
Some |
|
Furylfuramide isomerase |
Is a |
False |
Enzyme |
Inferred relationship |
Some |
|
Farnesol 2-isomerase |
Is a |
False |
Enzyme |
Inferred relationship |
Some |
|
3-carboxy-cis,cis-muconate cycloisomerase |
Is a |
False |
Enzyme |
Inferred relationship |
Some |
|
Phenylpyruvate tautomerase |
Is a |
False |
Enzyme |
Inferred relationship |
Some |
|
Protein disulfide-isomerase |
Is a |
False |
Enzyme |
Inferred relationship |
Some |
|
Isopentenyl-diphosphate delta-isomerase |
Is a |
False |
Enzyme |
Inferred relationship |
Some |
|
D-lyxose ketol-isomerase (substance) |
Is a |
False |
Enzyme |
Inferred relationship |
Some |
|
Hydroxypyruvate isomerase |
Is a |
False |
Enzyme |
Inferred relationship |
Some |
|
Phosphoribosylanthranilate isomerase |
Is a |
False |
Enzyme |
Inferred relationship |
Some |
|
Allantoin racemase |
Is a |
False |
Enzyme |
Inferred relationship |
Some |
|
Thiocyanate isomerase |
Is a |
False |
Enzyme |
Inferred relationship |
Some |
|
Methylitaconate delta-isomerase |
Is a |
False |
Enzyme |
Inferred relationship |
Some |
|
Galactose-6-phosphate isomerase (substance) |
Is a |
False |
Enzyme |
Inferred relationship |
Some |
|
Adenosine diphosphate-glyceromanno-heptose 6-epimerase (substance) |
Is a |
False |
Enzyme |
Inferred relationship |
Some |
|
Glucuronate isomerase |
Is a |
False |
Enzyme |
Inferred relationship |
Some |
|
Steroid delta-isomerase |
Is a |
False |
Enzyme |
Inferred relationship |
Some |
|
Oxaloacetate tautomerase |
Is a |
False |
Enzyme |
Inferred relationship |
Some |
|
Isopiperitenone delta-isomerase |
Is a |
False |
Enzyme |
Inferred relationship |
Some |
|
Isobutyryl-CoA mutase |
Is a |
False |
Enzyme |
Inferred relationship |
Some |
|
Tetrahydroxypteridine cycloisomerase |
Is a |
False |
Enzyme |
Inferred relationship |
Some |
|
Dopachrome isomerase |
Is a |
False |
Enzyme |
Inferred relationship |
Some |
|
Carboxy-cis,cis-muconate cyclase |
Is a |
False |
Enzyme |
Inferred relationship |
Some |
|
Thromboxane synthase |
Is a |
False |
Enzyme |
Inferred relationship |
Some |
|
Styrene-oxide isomerase |
Is a |
False |
Enzyme |
Inferred relationship |
Some |
|
Geranyl-diphosphate cyclase |
Is a |
False |
Enzyme |
Inferred relationship |
Some |
|
Arginine racemase |
Is a |
False |
Enzyme |
Inferred relationship |
Some |
|
Precorrin-8X methylmutase |
Is a |
False |
Enzyme |
Inferred relationship |
Some |
|
Dodecenoyl -CoA delta-isomerase |
Is a |
False |
Enzyme |
Inferred relationship |
Some |
|
L-rhamnose isomerase |
Is a |
False |
Enzyme |
Inferred relationship |
Some |
|
Linoleate isomerase |
Is a |
False |
Enzyme |
Inferred relationship |
Some |
|
Phosphoenolpyruvate mutase |
Is a |
False |
Enzyme |
Inferred relationship |
Some |
|
Lysine racemase |
Is a |
False |
Enzyme |
Inferred relationship |
Some |
|
Phenylalanine racemase (ATP-hydrolysing) |
Is a |
False |
Enzyme |
Inferred relationship |
Some |
|