96058005: Cilastatin (substance)

SNOMED CT Concept\Substance\...

\Substance categorized by disposition\Substance with effector mechanism of action (substance)\Enzyme inhibitor\Hydrolase inhibitor\Peptide hydrolase inhibitor\Cilastatin

\A grouper concept for substances that are used in medicinal products for medical treatment, and also psychoactive substances that have few or no legitimate medical uses or that are not legally available to the person using them.\Cilastatin

\Substance categorised by structure\Chemical\Chemical categorized by structure (substance)\...

\Sulfur and/or sulfur compound\Sulfur compound\Organic sulfur compound\Mercaptan compound\Organic sulfide compound\Cilastatin

\Organic compound\Organic sulfur compound\Mercaptan compound\Organic sulfide compound\Cilastatin

Status: current, Not sufficiently defined by necessary conditions definition status (core metadata concept). Date: 31-Jan 2002. Module: SNOMED CT core

Descriptions:

Expanded Value Set

Outbound Relationships	Type	Target	Active	Characteristic	Refinability	Group	Values
Cilastatin	Is a	Medicinal product containing beta-lactam and acting as antibacterial agent (product)	false	Inferred relationship	Some
Cilastatin	Is a	Fatty acid	false	Inferred relationship	Some
Cilastatin	Is a	allergène médicamenteux	false	Inferred relationship	Some
Cilastatin	Is a	Peptide hydrolase inhibitor	true	Inferred relationship	Some
Cilastatin	This attribute specifies the behavior that a substance will exhibit or participate in, given the appropriate context.	Peptide hydrolase inhibitor (disposition)	true	Inferred relationship	Some
Cilastatin	Is a	produit chimique catégorisé selon sa fonction	false	Inferred relationship	Some
Cilastatin	Is a	Enzyme inhibitor	false	Inferred relationship	Some
Cilastatin	Is a	Organic sulfide compound	true	Inferred relationship	Some
Cilastatin	Is a	A grouper concept for substances that are used in medicinal products for medical treatment, and also psychoactive substances that have few or no legitimate medical uses or that are not legally available to the person using them.	true	Inferred relationship	Some

Inbound Relationships	Type	Active	Source	Characteristic	Refinability	Group
Product containing cilastatin and imipenem (medicinal product)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Cilastatin	Inferred relationship	Some	2
Imipenem 500mg/cilastatin 500mg powder for infusion solution vial	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Cilastatin	Inferred relationship	Some
Product containing precisely cilastatin (as cilastatin sodium) 500 milligram and imipenem (as imipenem monohydrate) 500 milligram/1 vial powder for conventional release suspension for injection	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Cilastatin	Inferred relationship	Some
Imipenem 500mg/cilastatin 500mg powder for infusion solution transfer vial	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Cilastatin	Inferred relationship	Some
Cilastatin (as cilastatin sodium) 250 mg and imipenem anhydrous (as imipenem) 250 mg powder for solution for injection vial	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Cilastatin	Inferred relationship	Some
Imipenem 750mg/cilastatin 750mg powder for injection solution vial	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Cilastatin	Inferred relationship	Some
Product containing cilastatin (medicinal product)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Cilastatin	Inferred relationship	Some	1
Cilastatin- and imipenem-containing product in parenteral dose form	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Cilastatin	Inferred relationship	Some	2
Cilastatin sodium (substance)	Is a	False	Cilastatin	Inferred relationship	Some
Product containing precisely cilastatin (as cilastatin sodium) 500 milligram and imipenem (as imipenem monohydrate) 500 milligram/1 vial powder for conventional release suspension for injection	This attribute represents an ingredient that is the part of the active ingredient that the strength of a given product is based upon.	False	Cilastatin	Inferred relationship	Some	1
Cilastatin sodium (substance)	This attribute indicates that the concept is a structural modification of another concept, and that the substance's intrinsic physicochemical properties remain unchanged.	True	Cilastatin	Inferred relationship	Some
Product containing only cilastatin (medicinal product)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Cilastatin	Inferred relationship	Some	1
Cilastatin and imipenem only product	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Cilastatin	Inferred relationship	Some	2
Product containing only cilastatin and imipenem in parenteral dose form (medicinal product form)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Cilastatin	Inferred relationship	Some	2
Product containing precisely cilastatin (as cilastatin sodium) 500 milligram and imipenem anhydrous (as imipenem) 500 milligram/1 vial powder for conventional release solution for injection (clinical drug)	This attribute represents an ingredient that is the part of the active ingredient that the strength of a given product is based upon.	True	Cilastatin	Inferred relationship	Some	2
Cilastatin (as cilastatin sodium) 250 mg and imipenem anhydrous (as imipenem) 250 mg powder for solution for injection vial	This attribute represents an ingredient that is the part of the active ingredient that the strength of a given product is based upon.	True	Cilastatin	Inferred relationship	Some	2
Product containing cilastatin and imipenem and relebactam (medicinal product)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Cilastatin	Inferred relationship	Some	3
Product containing only cilastatin and imipenem and relebactam (medicinal product)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Cilastatin	Inferred relationship	Some	3
Product containing cilastatin and imipenem and relebactam in parenteral dose form (medicinal product form)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Cilastatin	Inferred relationship	Some	3
Cilastatin and imipenem and relebactam only product in parenteral dose form	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Cilastatin	Inferred relationship	Some	3
Product containing precisely cilastatin (as cilastatin sodium) 500 milligram and imipenem 500 milligram/1 vial powder for conventional release suspension for injection (clinical drug)	This attribute represents an ingredient that is the part of the active ingredient that the strength of a given product is based upon.	True	Cilastatin	Inferred relationship	Some	2
Product containing precisely cilastatin (as cilastatin sodium) 500 milligram and imipenem 500 milligram/1 vial powder for conventional release solution for infusion (clinical drug)	This attribute represents an ingredient that is the part of the active ingredient that the strength of a given product is based upon.	True	Cilastatin	Inferred relationship	Some	2
Cilastatin (as cilastatin sodium) 500 mg and imipenem 500 mg and relebactam 250 mg powder for solution for infusion vial	This attribute represents an ingredient that is the part of the active ingredient that the strength of a given product is based upon.	True	Cilastatin	Inferred relationship	Some	3
Product containing precisely cilastatin (as cilastatin sodium) 500 milligram and imipenem 500 milligram/1 vial powder for conventional release solution for infusion and/or injection (clinical drug)	This attribute represents an ingredient that is the part of the active ingredient that the strength of a given product is based upon.	False	Cilastatin	Inferred relationship	Some	2

Reference Sets

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Id	Description	Lang	Type	Status	Case?	Module
159098019	Cilastatin	en	Synonym (core metadata concept)	Active	Entire term case insensitive (core metadata concept)	SNOMED CT core
840341010	Cilastatin (substance)	en	Fully specified name	Active	Entire term case insensitive (core metadata concept)	SNOMED CT core
51251000195111	cilastatina	it	Synonym (core metadata concept)	Active	Entire term case insensitive (core metadata concept)	SNOMED CT Switzerland NRC maintained Module
800761000172110	cilastatine	fr	Synonym (core metadata concept)	Active	Entire term case insensitive (core metadata concept)	SNOMED CT Switzerland NRC maintained Module
65471000195112	Cilastatin	de	Synonym (core metadata concept)	Active	Entire term case sensitive (core metadata concept)	SNOMED CT Switzerland NRC maintained Module