96303004: Lovastatin (substance)

SNOMED CT Concept\Substance\...

\Substance categorized by disposition\Substance with effector mechanism of action (substance)\Enzyme inhibitor\HMG-CoA reductase inhibitor\Lovastatin

\A grouper concept for substances that are used in medicinal products for medical treatment, and also psychoactive substances that have few or no legitimate medical uses or that are not legally available to the person using them.\Cardiovascular agent (substance)\Antilipemic agent (substance)\HMG-CoA reductase inhibitor\Lovastatin

\Substance categorised by structure\Chemical\Chemical categorized by structure (substance)\Organic compound\Hydrocarbon\Aromatic hydrocarbon\Polyaromatic hydrocarbon\Naphthalene\Lovastatin

Status: current, Not sufficiently defined by necessary conditions definition status (core metadata concept). Date: 31-Jan 2002. Module: SNOMED CT core

Descriptions:

Expanded Value Set

Outbound Relationships	Type	Target	Active	Characteristic	Refinability	Group	Values
Lovastatin	Is a	Product containing 3-hydroxy-3-methylglutaryl-coenzyme A reductase inhibitor (product)	false	Inferred relationship	Some
Lovastatin	Is a	HMG-CoA reductase inhibitor	true	Inferred relationship	Some
Lovastatin	Is a	Naphthalene	true	Inferred relationship	Some
Lovastatin	This attribute specifies the behavior that a substance will exhibit or participate in, given the appropriate context.	HMG-CoA reductase inhibitor	true	Inferred relationship	Some
Lovastatin	Is a	produit chimique catégorisé selon sa fonction	false	Inferred relationship	Some
Lovastatin	Is a	allergène médicamenteux	false	Inferred relationship	Some

Inbound Relationships	Type	Active	Source	Characteristic	Refinability	Group
Lovastatin 10 mg oral tablet	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Lovastatin	Inferred relationship	Some
Lovastatin 20 mg oral tablet	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Lovastatin	Inferred relationship	Some
Lovastatin 40 mg oral tablet	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Lovastatin	Inferred relationship	Some
Product containing lovastatin (medicinal product)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Lovastatin	Inferred relationship	Some	1
Lovastatin 20 mg and nicotinic acid 500 mg oral tablet	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Lovastatin	Inferred relationship	Some
Product containing precisely lovastatin 20 milligram and nicotinic acid 750 milligram/1 each conventional release oral tablet (clinical drug)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Lovastatin	Inferred relationship	Some
Lovastatin 20 mg and nicotinic acid 1 g oral tablet	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Lovastatin	Inferred relationship	Some
Product containing lovastatin and nicotinic acid (medicinal product)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Lovastatin	Inferred relationship	Some	2
Lovastatin 10mg m/r tablet	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Lovastatin	Inferred relationship	Some
Lovastatin 20mg m/r tablet	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Lovastatin	Inferred relationship	Some
Lovastatin 40mg m/r tablet	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Lovastatin	Inferred relationship	Some
Lovastatin 60mg m/r tablet	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Lovastatin	Inferred relationship	Some
Lovastatin 40 mg and nicotinic acid 1 g oral tablet	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Lovastatin	Inferred relationship	Some
Allergy to lovastatin	Causative agent (attribute)	True	Lovastatin	Inferred relationship	Some	1
Adverse reaction caused by lovastatin	Causative agent (attribute)	True	Lovastatin	Inferred relationship	Some	1
Lovastatin 20 mg and nicotinic acid 500 mg oral tablet	This attribute represents an ingredient that is the part of the active ingredient that the strength of a given product is based upon.	True	Lovastatin	Inferred relationship	Some	2
Product containing precisely lovastatin 20 milligram and nicotinic acid 750 milligram/1 each conventional release oral tablet (clinical drug)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Lovastatin	Inferred relationship	Some	2
Product containing precisely lovastatin 20 milligram and nicotinic acid 750 milligram/1 each conventional release oral tablet (clinical drug)	This attribute represents an ingredient that is the part of the active ingredient that the strength of a given product is based upon.	True	Lovastatin	Inferred relationship	Some	2
Lovastatin 20 mg and nicotinic acid 1 g oral tablet	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Lovastatin	Inferred relationship	Some	2
Lovastatin 20 mg and nicotinic acid 1 g oral tablet	This attribute represents an ingredient that is the part of the active ingredient that the strength of a given product is based upon.	True	Lovastatin	Inferred relationship	Some	2
Lovastatin 40 mg and nicotinic acid 1 g oral tablet	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Lovastatin	Inferred relationship	Some	2
Lovastatin 40 mg and nicotinic acid 1 g oral tablet	This attribute represents an ingredient that is the part of the active ingredient that the strength of a given product is based upon.	True	Lovastatin	Inferred relationship	Some	2
Lovastatin 10 mg oral tablet	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Lovastatin	Inferred relationship	Some	1
Lovastatin 10 mg oral tablet	This attribute represents an ingredient that is the part of the active ingredient that the strength of a given product is based upon.	True	Lovastatin	Inferred relationship	Some	1
Lovastatin 20 mg oral tablet	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Lovastatin	Inferred relationship	Some	1
Lovastatin 20 mg oral tablet	This attribute represents an ingredient that is the part of the active ingredient that the strength of a given product is based upon.	True	Lovastatin	Inferred relationship	Some	1
Lovastatin 40 mg oral tablet	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Lovastatin	Inferred relationship	Some	1
Lovastatin 40 mg oral tablet	This attribute represents an ingredient that is the part of the active ingredient that the strength of a given product is based upon.	True	Lovastatin	Inferred relationship	Some	1
Lovastatin 20 mg and nicotinic acid 500 mg oral tablet	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Lovastatin	Inferred relationship	Some	1
Lovastatin 20 mg and nicotinic acid 500 mg oral tablet	This attribute represents an ingredient that is the part of the active ingredient that the strength of a given product is based upon.	False	Lovastatin	Inferred relationship	Some	1
Lovastatin 20mg prolonged-release oral tablet	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Lovastatin	Inferred relationship	Some
Lovastatin 40mg prolonged-release oral tablet	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Lovastatin	Inferred relationship	Some
Lovastatin 10mg prolonged-release oral tablet	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Lovastatin	Inferred relationship	Some
Lovastatin 60mg prolonged-release oral tablet	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Lovastatin	Inferred relationship	Some
Lovastatin 10 mg oral tablet	The most specific description of a substance present in the manufactured dose form, before any dilution or transformation. It includes modifiers, such as salts, esters, polymers (e.g. pegylation), and/or solvates (including waters of hydration).	True	Lovastatin	Inferred relationship	Some	1
Lovastatin 20 mg oral tablet	The most specific description of a substance present in the manufactured dose form, before any dilution or transformation. It includes modifiers, such as salts, esters, polymers (e.g. pegylation), and/or solvates (including waters of hydration).	True	Lovastatin	Inferred relationship	Some	1
Lovastatin 40 mg oral tablet	The most specific description of a substance present in the manufactured dose form, before any dilution or transformation. It includes modifiers, such as salts, esters, polymers (e.g. pegylation), and/or solvates (including waters of hydration).	True	Lovastatin	Inferred relationship	Some	1
Lovastatin 40 mg and nicotinic acid 1 g oral tablet	The most specific description of a substance present in the manufactured dose form, before any dilution or transformation. It includes modifiers, such as salts, esters, polymers (e.g. pegylation), and/or solvates (including waters of hydration).	True	Lovastatin	Inferred relationship	Some	2
Lovastatin 20 mg and nicotinic acid 500 mg oral tablet	The most specific description of a substance present in the manufactured dose form, before any dilution or transformation. It includes modifiers, such as salts, esters, polymers (e.g. pegylation), and/or solvates (including waters of hydration).	True	Lovastatin	Inferred relationship	Some	2
Product containing precisely lovastatin 20 milligram and nicotinic acid 750 milligram/1 each conventional release oral tablet (clinical drug)	The most specific description of a substance present in the manufactured dose form, before any dilution or transformation. It includes modifiers, such as salts, esters, polymers (e.g. pegylation), and/or solvates (including waters of hydration).	True	Lovastatin	Inferred relationship	Some	2
Lovastatin 20 mg and nicotinic acid 1 g oral tablet	The most specific description of a substance present in the manufactured dose form, before any dilution or transformation. It includes modifiers, such as salts, esters, polymers (e.g. pegylation), and/or solvates (including waters of hydration).	True	Lovastatin	Inferred relationship	Some	2
Lovastatin-containing product in oral dose form	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Lovastatin	Inferred relationship	Some	1
Lovastatin- and nicotinic acid-containing product in oral dose form	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Lovastatin	Inferred relationship	Some	2
Product containing only lovastatin (medicinal product)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Lovastatin	Inferred relationship	Some	1
Product containing only lovastatin and nicotinic acid (medicinal product)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Lovastatin	Inferred relationship	Some	2
Product containing only lovastatin in oral dose form (medicinal product form)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Lovastatin	Inferred relationship	Some	1
Product containing only lovastatin and nicotinic acid in oral dose form (medicinal product form)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Lovastatin	Inferred relationship	Some	2

Reference Sets

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Id	Description	Lang	Type	Status	Case?	Module
159404017	Lovastatin	en	Synonym (core metadata concept)	Active	Entire term case insensitive (core metadata concept)	SNOMED CT core
159405016	Mevinolin	en	Synonym (core metadata concept)	Active	Entire term case insensitive (core metadata concept)	SNOMED CT core
159406015	Monacolin K	en	Synonym (core metadata concept)	Active	Only initial character case insensitive (core metadata concept)	SNOMED CT core
840639018	Lovastatin (substance)	en	Fully specified name	Active	Entire term case insensitive (core metadata concept)	SNOMED CT core
1842851000195118	lovastatina	it	Synonym (core metadata concept)	Active	Entire term case sensitive (core metadata concept)	SNOMED CT Switzerland NRC maintained Module
4736691000241119	lovastatine	fr	Synonym (core metadata concept)	Active	Entire term case insensitive (core metadata concept)	SNOMED CT Switzerland NRC maintained Module
2330521000195114	Lovastatin	de	Synonym (core metadata concept)	Active	Entire term case insensitive (core metadata concept)	SNOMED CT Switzerland NRC maintained Module